乳腺癌术后癌症复发恐惧与夫妻支持和生活质量的关系

Fear of cancer recurrence and its relationship with couple support and quality of life in breast cancer patients undergoing surgery

目的:分析乳腺癌术后癌症复发恐惧与夫妻支持和生活质量的关系。方法:选取乳腺癌术后病人769例作为研究对象,使用疾病进展恐惧简化量表(FoP-Q-SF)、夫妻支持问卷(CSQ)、癌症病人生命质量测定量表(FACT-G)对病人进行问卷调查,分析FoP-Q-SF与CSQ、FACT-G的关系。结果:问卷调查显示,乳腺癌术后病人癌症复发恐惧心理发生率为52.67%(405/769)。Pearson相关分析显示,乳腺癌术后病人FoP-Q-SF得分与CSQ得分、FACT-G得分均呈明显负相关关系(P<0.01),CSQ得分与FACT-G得分呈明显正相关关系(P<0.01)。Logistic回归分析显示,年龄<40岁(OR=3.674)、临床分期Ⅲa期(OR=3.115)、CSQ得分≤49.29分(OR=3.843)、FACT-G得分≤41.36分(OR=2.774)是乳腺癌术后癌症复发恐惧的独立危险因素(P<0.01)。结论:乳腺癌术后病人癌症复发恐惧水平较高,夫妻支持和生活质量是其影响因素,临床可据此制定干预措施以降低病人的癌症复发恐惧。

Objective:To analyze the status of fear of cancer recurrence and its relationship with couple support and quality of life in breast cancer patients undergoing surgery.Methods:A total of 769 postoperative patients with breast cancer were selected as the research object.The patients were investigated by using the fear of progression questionnaire-short form(FoP-Q-SF),couple support questionnaire(CSQ),and functional assessment of cancer therapy-generic scale(FACT-G),and the relationship between FoP-Q-SF score and CSQ score or FACT-G score was also analyzed.Results:The questionnaire survey results showed that the incidence of fear of cancer recurrence was 52.67%(405/769)in patients with breast cancer undergoing surgery.Pearson correlation analysis revealed a significant negative correlation between FoP-Q-SF score and CSQ score or FACT-G score(P<0.01),and a significant positive correlation between CSQ score and FACT-G score(P<0.01).Logistic regression analysis further showed that age<40 years old(O R=3.674),clinical stageⅢa(OR=3.115),CSQ score≤49.29 points(OR=3.843),and FACT-G score≤41.36 points(OR=2.774)were independent risk factors for fear of cancer recurrence in postoperative breast cancer patients(all P<0.01).Conclusions:Postoperative patients with breast cancer have a high level of fear of cancer recurrence,which is correlated with couple support and quality of life.Therefore,clinical intervention targeting these factors could be helpful in reducing the fear of cancer recurrence for postoperative breast cancer patients.