超声中心肌做功参数的正常参考值范围及临床应用研究进展

Research progress on normal reference value range and clinical applications of ultrasonic myocardial work parameters

心肌做功(MW)技术通过结合二维斑点追踪超声心动图与无创肱动脉血压得到左室压力应变环,产生四个主要的参数评价心肌收缩功能。相比于目前临床上广泛应用的左室射血分数,MW在应变基础上具有更好地减少负荷对心肌功能评估的影响、提供整体与局部心肌功能信息和早期识别心血管疾病心肌功能受损情况等特点。本文首先介绍了MW原理及主要参数,归纳不同人群中MW参数正常参考值范围研究结果,对MW应用于临床心血管疾病心肌收缩功能评价的代表性研究成果做出综述,最后分析了MW的局限性,并对该技术良好的应用前景作出展望。

Myocardial work(MW)technology obtains the left ventricular pressure-strain loop by combining two-dimensional speckle tracking echocardiography with noninvasive brachial artery blood pressure,and produces four main parameters to evaluate myocardial systolic function.Compared with the left ventricular ejection fraction,which is widely used in clinic at present,MW has the characteristics of better reducing the impact of load on the evaluation of myocardial function on the basis of strain,providing global and segmental myocardial function information,and early identifying the damage of myocardial function in cardiovascular diseases.This paper first introduces the principle and main parameters of MW,summarizes the research results of the normal reference value range of MW parameters in different populations,then the representative research results of MW applied to the evaluation of myocardial systolic function in clinical cardiovascular diseases are summarized,and finally analyzes the limitations of MW,as well as prospects the good application prospect of MW technology.