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针药复合麻醉对高龄髋关节置换患者免疫功能与认知功能的影响 被引量:1

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摘要 目的探讨针药复合麻醉对高龄髋关节置换患者免疫功能与认知功能的影响,为临床上合理选择麻醉方法提供参考。方法2018年5月至2021年3月选择在我院进行髋关节置换的高龄患者66例作为研究对象,根据随机信封抽签原则把患者分为复合组与对照组各33例。术后对照组给予传统药物镇痛麻醉,复合组在对照组镇痛麻醉的基础上予超声引导下针刀镇痛,观察与调查患者术后免疫功能与认知功能情况。结果两组的性别、年龄、体重指数、术中出血量、手术时间等对比差异无统计学意义(P>0.05),复合组的术后下地时间、术后住院时间少于对照组(P<0.05)。复合组术后1 d、术后3 d与术后14 d的疼痛VAS评分都低于对照组(P<0.05)。复合组术后1 d、术后3 d与术后14 d的髋关节活动度都高于对照组(P<0.05)。复合组术后14 d的认知功能障碍发生率为3.0%,低于对照组的18.2%(P<0.05)。两组术后14 d的CD_(4)^(+)CD_(25)^(+)T和CD_(4)^(+)OX_(40)^(+)T细胞比例高于术后1 d(P<0.05),复合组高于对照组(P<0.05)。结论针药复合麻醉在高龄髋关节置换患者的应用能改善患者的免疫功能,降低术后认知功能障碍发生率,从而促进患者康复,提高镇痛水平。
作者 徐军 薛玉婷
出处 《贵州医药》 CAS 2022年第9期1440-1442,共3页 Guizhou Medical Journal
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