白内障患者术后发生角膜水肿的影响因素分析

Analysis on the Influencing Factors of Corneal Edema in Postoperative Patients with Cataract

目的分析白内障患者术后发生角膜水肿的相关影响因素。方法选取2020年1月至2021年10月在我院行手术治疗的100例白内障患者,观察患者术后2~3 d内角膜水肿发生情况,统计患者基线资料,经单因素和多因素分析找出导致白内障患者术后发生角膜水肿的相关因素。结果100例白内障患者术后发生角膜水肿19例,发生率为19.00%。发生组的晶状体核硬级别、糖尿病史、手术切口及术中玻璃体溢出与未发生组比较差异有统计学意义(P<0.05)。经Logistic回归分析结果显示,晶状体核硬Ⅲ~Ⅴ级、有糖尿病史、透明角膜切口及术中有玻璃体溢出是白内障患者术后发生角膜水肿的影响因素(OR>1,P<0.05)。结论白内障患者术后角膜水肿的发生与晶状体核硬Ⅲ~Ⅴ级、有糖尿病史、透明角膜切口及术中有玻璃体溢出等因素有关,临床可据此制定针对性干预方案,以降低术后角膜水肿发生率。

Objective To explore the influencing factors of corneal edema in postoperative patients with cataract.Methods 100 cataract patients with surgery in our hospital from January 2020 to October 2021 were selected,and the corneal edema within 2 to 3 days after surgery was observed.The baseline data of patients were counted,and the related factors leading to corneal edema in cataract patients were found out by univariate and multivariate analysis.Results Among 100 postoperative patients with cataract,19 cases had corneal edema,with the incidence of 19.00%.Statistical difference was found in the lens nucleus hardness level,diabetes history,surgical incision and vitreous body overflow between the occurrence group and non-occurrence group(P<0.05).Logistic regression analysis showed that lens nucleus hardnessⅢtoⅣ,diabetes history,clear corneal incision and intraoperative vitreous body overflow were the influencing factors of corneal edema in postoperative patients with cataract(OR>1,P<0.05).Conclusions Corneal edema after cataract surgery is related to the lens nucleus hardnessⅢtoⅣ,diabetes history,clear corneal incision and intraoperative vitreous body overflow.Based on this,targeted intervention plan can be formulated in order to reduce the incidence of postoperative corneal edema.