宫内高雄激素环境对子代健康的影响及其机制研究进展

Research progress in influence of intrauterine hyper androgen on offspring health and mechanisms

母体不良内分泌环境严重影响子代各系统生长发育。本文综述了近年来宫内高雄激素环境对子代健康影响的人群队列、动物实验以及相关机制研究,为未来高雄激素暴露与子代慢性疾病发生的研究方向、机制探寻、早期干预提供新视角。

Maternal adverse endocrine environment severely affects the growth and development of offspring.This article reviews relevant cohort studies and animal experiments on the influence of intrauterine hyper androgen on offspring health and the mechanisms,aiming to provide a new perspective for further research,mechanism exploration,and early interventions in this field.