5+2轻断食对超重/肥胖高血压患者的干预效果研究

The effect of intermittent energy restriction(5∶2 diet)in overweight/obese patients with hypertension

目的探讨5+2轻断食在超重/肥胖高血压患者中的降压和减重效果。方法选取2020年11月至2021年8月于嘉兴市第一医院接受治疗的86例超重/肥胖高血压患者为研究对象,按随机数字表法分为观察组和对照组,每组43例;观察组予5+2轻断食干预,对照组为正常饮食。随访12周,比较两组患者TG、TC、LDL-C、收缩压、舒张压和体重。结果两组患者第12周末TG、LDL-C差异均无统计学意义(均P>0.05);观察组TC低于对照组,差异有统计学意义(P<0.05)。观察组第4、8、12周末收缩压低于对照组,差异均有统计学意义(均P<0.05);观察组第8、12周末舒张压低于对照组,差异均有统计学意义(均P>0.05)。与对照组相比,观察组第12周末体重降低,差异有统计学意义(P<0.05)。结论5+2轻断食能有效降低超重/肥胖高血压患者的收缩压、舒张压和体重。

Objective To investigate the effect of intermittent energy restriction(5∶2 diet)in overweight/obese patients with hypertension.Methods A total of 86 overweight/obese patients with hypertension in the Department of Cardiology,Jiaxing First Hospital from November 2020 to August 2021 were selected for a prospective study.Patients were divided into study group(5:2 diet)and control group(ad libitum).The triglyceride,total cholesterol,low density lipoprotein,systolic pressure,diastolic pressure and weight were compared between two groups after 12-week follow-up.Results There was no significant difference in triglyceride and low density lipoprotein between two groups(all P>0.05).Compared with control group,the body weight,total cholesterol,systolic pressure and diastolic pressure of patients in study group was significantly lower after 12-week,intermittent energy restriction(all P<0.05).Conclusion The intermittent energy restriction(5∶2 diet)is effective to decrease the systolic pressure,diastolic pressure and weight of overweight/obese patients with hypertension.