八段锦联合经颅直流电刺激治疗脑卒中后轻度认知功能障碍临床研究

Clinical Study on Baduanjin Combined with Transcranial Direct Current Stimulation for Mild Cognitive Impairment After Stroke

目的:观察八段锦联合经颅直流电刺激治疗脑卒中后轻度认知功能障碍的临床疗效。方法:以随机数字表法将94例脑卒中后轻度认知功能障碍患者分为对照组和观察组各47例。对照组给予经颅直流电刺激治疗,观察组在对照组基础上进行八段锦锻炼。比较2组临床疗效,观察2组治疗前后认知功能、生活活动能力及神经电生理指标的变化。结果:观察组总有效率91.49%,高于对照组74.47%(P<0.05)。治疗后,2组蒙特利尔认知评估量表(MoCA)、简易智能状态量表(MMSE)、功能独立性评定量表(FIM)、改良Barthel指数评定量表(MBI)评分均较治疗前升高(P<0.05),观察组MoCA、MMSE、FIM、MBI评分均高于对照组(P<0.05)。治疗后,2组P300潜伏期均较治疗前缩短(P<0.05),P300波幅均较治疗前增大(P<0.05);观察组P300潜伏期短于对照组(P<0.05),P300波幅大于对照组(P<0.05)。结论:八段锦联合经颅直流电刺激治疗脑卒中后轻度认知功能障碍疗效确切,可改善患者的认知功能和神经电生理指标,提高其生活活动能力。

Objective: To observe the clinical effect of Baduanjin combined with transcranial direct current stimulation for mild cognitive impairment after stroke. Methods:A total of 94 cases of patients with mild cognitive impairment after stroke were divided into the control group and the observation group according to the random number table method,with 47 cases in each group. The control group was treated with transcranial direct current stimulation,and the observation group was intervened with Baduanjin based on the treatment of the control group. The clinical effects in the two groups were compared. Before and after treatment, the changes in cognitive function, activities of daily living and nerve electrophysiology indexes in the two groups were observed. Results:The total effective rate was 91.49% in the observation group,higher than that of 74.47% in the control group(P<0.05). After treatment,the scores of Montreal Cognitive Assessment(MoCA), Mini-Mental Status Exam(MMSE), Functional Independence Measure(FIM) and Modified Barthel Index(MBI) in the two groups were increased when compared with those before treatment(P<0.05),and the scores of MoCA,MMSE,FIM and MBI in the observation group were higher than those in the control group(P<0.05). After treatment,P300 latency in the two groups were shortened when compared with those before treatment(P<0.05),and P300 amplitude were increased(P<0.05);the P300 latency in the observation group was shorter than that in the control group(P<0.05),and the P300amplitude was larger(P<0.05). Conclusion:Baduanjin combined with transcranial direct current stimulation has a definite curative effect in treating patients with mild cognitive impairment after stroke, which can improve cognitive function,nerve electrophysiology indexes and activities of daily living.