GP化疗方案辅助手术治疗对非小细胞肺癌手术患者临床疗效及生活质量的影响研究

Effect of GP Chemotherapy Regimen Adjuvant Surgical Treatment on the Clinical Efficacy and Quality of Life of Patients with Non-small Cell Lung Cancer Surgery

目的研究GP化疗方案辅助手术治疗非小细胞肺癌手术患者临床分析。方法选择非小细胞肺癌患者102例,随机分为两组,观察组和对照组各51例。对照组仅手术治疗。观察组联合GP化疗方案辅助手术方案,比较组间病人疗效、计算生活质量评分差异。结果观察组病人治疗后的总有效率为84.31%,显著高于对照组58.82%,P<0.05;术后15 d、50 d和180 d时观察组患者KPS评分、生存率均显著高于对照组,差异显著,P<0.05。结论对非小细胞肺癌患者术前采用GP辅助化疗,可显著提高患者临床疗效,改善患者生活质量。

Objective To study the clinical analysis of GP chemotherapy in adjuvant surgical treatment of non-small cell lung cancer patients.Methods A total of 102 patients with non-small cell lung cancer in our hospital were selected and randomly divided into two groups,with 51 cases in the observation group and 51 cases in the control group.The control group was treated with surgery only.The observation group was combined with GP chemotherapy to assist the surgical plan to compare the efficacy of patients between the groups and calculate the difference in quality of life scores.Results The total effective rate of patients in the observation group after treatment was 84.31%,which was significantly higher than 58.82%in the control group,P<0.05;the KPS score and survival rate of the observation group were significantly higher than those in the control group at 15 days,50 days and 180 days after surgery.,The difference is significant,P<0.05.Conclusions Preoperative GP adjuvant chemotherapy for patients with non-small cell lung cancer can significantly improve the clinical efficacy and quality of life of patients.