明胶海绵颗粒、聚乙烯醇栓塞微球在大咯血支气管动脉栓塞治疗中的应用效果比较

Comparison of the application effects of gelfoam particles and polyvinyl alcohol microsphere in bronchial artery embolization treatment for massive hemoptysis

目的比较明胶海绵颗粒、聚乙烯醇栓塞微球在大咯血支气管动脉栓塞治疗中的应用效果。方法选择宝鸡市中医医院2019年6月至2020年3月收治的200例行支气管动脉栓塞治疗的大咯血患者作为研究对象,根据随机抽签分组原则将其分为对照组和观察组,各100例。对照组采用聚乙烯醇栓塞微球进行栓塞,观察组采用明胶海绵颗粒进行栓塞。比较两组的治疗效果。结果观察组的治疗总有效率高于对照组(P<0.05)。观察组治疗后1个月的并发症总发生率及治疗后6个月的复发率均低于对照组(P<0.05)。治疗后,观察组的动脉血氧分压(PaO_(2))高于对照组,呼吸频率(RR)低于对照组(P<0.05)。观察组的24 h止血率高于对照组(P<0.05)。治疗后1个月,观察组的凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)及凝血酶时间(TT)均短于对照组(P<0.05)。结论在大咯血支气管动脉栓塞治疗中采用明胶海绵颗粒可获得更显著的临床效果。

Objective To compare the application effects of gelfoam particles and polyvinyl alcohol microsphere in bronchial artery embolization treatment for massive hemoptysis.Methods Two hundred patients with massive hemoptysis treated by bronchial artery embolization in Traditional Chinese Medicine Hospital of Baoji from June 2019 to March 2020were selected as the research objects and divided into control group and observation group according to the principle of random lot drawing,with 100 cases in each group.The control group was embolized with polyvinyl alcohol microsphere,and the observation group was embolized with gelfoam particles.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05).The total incidence of complications at 1 month after treatment and the recurrence rate at 6 months after treatment in the observation group were lower than those in the control group(P<0.05).After treatment,arterial partial pressure of oxygen(PaO_(2))in the observation group was higher than that in the control group,and respiratory rate(RR)was lower than that in the control group(P<0.05).The 24 h hemostatic rate of the observation group was higher than that of the control group(P<0.05).One month after treatment,prothrombin time(PT),activated partial thromboplastin time(APTT)and thrombin time(TT)in the observation group were shorter than those in the control group(P<0.05).Conclusion Gelfoam particles applied in bronchial artery embolization treatment for massive hemoptysis can obtain more significant clinical effect.