吲哚菁绿荧光成像技术在宫颈癌根治术中的应用进展

Application Progress of Indocyanine Green Fluorescence Imaging Technique in Radical Resection of Cervical Cancer

宫颈癌是我国女性最常见的生殖系统恶性肿瘤,根治性手术是早期宫颈癌的主要治疗方式,但手术范围大,技术难度高,术后可能出现的并发症多。吲哚菁绿(indocyanine green,ICG)荧光成像技术在外科手术中的应用已十分广泛,并有越来越多的研究表明其在宫颈癌根治术中也展现出巨大的应用前景,在示踪前哨淋巴结、识别盆腔神经、评估子宫血流灌注和保护输尿管等方面发挥着积极作用。这不仅提高了术中肿瘤切除的准确性,还能实现重要解剖结构的可视化,进一步减少术后并发症、改善预后,使患者获益。但目前ICG荧光成像技术在宫颈癌手术治疗中的应用尚处于初步阶段,仍需进一步扩大样本去验证其安全性及有效性。

Cervical cancer is one of the most common malignant tumors of reproductive system in China.Radical surgery is the main treatment of early cervical cancer.However,the scope of operation is wide and the technical difficulty is high.There may be many postoperative complications.The indocyanine green(ICG)fluorescence imaging technique has been widely used in surgery,and more and more studies have shown that it also shows a great application prospect in the radical resection of cervical cancer.This technique may play an active role in tracing sentinel lymph nodes,identifying pelvic nerve,evaluating uterine blood perfusion,protecting ureter and so on.This can not only improve the accuracy of intraoperative tumor resection,but also achieve the visualization of important anatomical structures,further reduce postoperative complications and improve prognosis,which can bring great benefits to patients.However,the application of ICG fluorescence imaging technique in the surgical treatment of cervical cancer is still in the initial stage.The safety and effectiveness of this technique need to be tested by the more application in clinical practice.