妊娠期糖尿病患者发生自发性早产相关因素研究

Study on Related Factors of Spontaneous Preterm Birth in Patients with Gestational Diabetes Mellitus

目的:探讨妊娠期糖尿病(GDM)患者发生自发性早产的影响因素.方法:收集2020年2月至2021年2月武陟县人民医院发生自发性早产的66例GDM患者临床资料,纳入发生组,另收集同期未发生自发性早产的66例GDM患者临床资料,纳入未发生组.查阅并记录患者临床资料,分析GDM患者发生自发性早产的影响因素.结果:发生组空腹血糖(FBG)、既往流产史、未足月胎膜早破、合并高血压与未发生组相比较,差异有统计学意义(P<0.05);经Logistic回归显示,FBG水平高、有既往流产史、未足月胎膜早破、合并高血压是GDM患者发生自发性早产的独立危险因素(OR>1,P<0.05).结论:GDM发生自发性早产可能与FBG水平高、有既往流产史、未足月胎膜早破、合并高血压等因素有关,可针对上述因素进行干预,以此降低自发性早产的发生率.

Objective:To explore influencing factors of spontaneous preterm birth in patients with gestational diabetes mellitus(GDM).Methods:The clinical data of 66 patients with GDM who had spontaneous preterm birth in Wuzhi County People's Hospital from February 2020 to February 2021 were collected and included in the occurrence group.Another 66 patients with CDM who did not have spontaneous preterm birth during the same period were collected and included in the non occurrence group.The clinical data of patients were reviewed and recorded,and the influencing factors of spontaneous preterm birth in patients with GDM were analyzed.Results:The difference in fasting blood glucose(FBG),previous abortion history,premature rupture of membranes and hypertension beteen the patients in the occurrence group and the non occurrence group was statistically significant(P<0.05);the results of Logistic regression showed that high level of FBG,history of previous abortion,preterm premature rupture of membranes,and hypertension were risk factors for spontaneous preterm labor in patients with GDM(OR>1,P<0.05).Conclusion:Spontaneous preterm labor in patients with GDM may be related to factors such as high FBG level,history of previous abortion,premature rupture of membranes,hypertension and other factors.Intervention can be carried out according to the above factors to reduce the incidence of spontaneous preterm birth.