基于数据挖掘中药治疗原发性痛经的用药规律研究

Study on the Medication Law of Traditional Chinese Medicine in Treating Primary DysmenorrheaBased on Data Mining

目的分析中药治疗原发性痛经的用药规律。方法检索中国知网(CNKI)、万方数据(WANFANG DATA)自建库起至2021年10月30日中治疗原发性痛经的中药汤剂,筛选其中的处方资料,通过“古今医案云平台V2.3.5”进行频数、四气五味、归经、关联和聚类分析。结果最终纳入处方143首,包含中药144味,主归肝、脾、心、肾经,其中使用频次较高的药物是当归、芍药、延胡索、川芎、香附等;使用较多的关联组合有:当归-芍药、当归-川芎、延胡索-当归、延胡索-芍药、川芎-芍药等。结论原发性痛经的治疗以活血化瘀、补血为主,辅以补气、行气、散寒。本研究为原发性痛经的临床用药提供了参考。

Objective:To analyze the medication law of traditional Chinese medicine in the treatment of primary dysmenorrhea.Methods:The TCM decoction for treating primary dysmenorrhea was retrieved from CNKI and WANFANG DATA from the self-built database to October 30,2021,and the prescription data were screened.The frequency,four-qi and five-flavor,channel tropism,association and cluster analysis were performed through Ancient and Modern Medical Record Cloud Platform V2.3.5.Results:A total of 143 prescriptions were included,including 144 TCM flavors,which mainly returned to the liver,spleen,heart and kidney meridian.The most frequently used drugs were Angelica sinensis,Peony,Corydalis tuber,Ligusticum and Rhizoma cyperi,etc.The most commonly used association combinations are Angelica-peony,Angelica-Ligusticum,Corydalis-Peony Ligusticum-Peony,etc.Conclusion:The treatment of primary dysmenorrhea is mainly based on activating blood circulation,removing blood stasis and tonifying blood,supplemented by tonifying qi,promoting qi and dispersing cold.This study provides a reference for the clinical medication of primary dysmenorrhea.