BNCT02加速器设计及离子源调试

Designing of BNCT02 Accelerator and Commissioning of ECR Ion Source

硼中子俘获治疗(BNCT)是一种安全的二元靶向放疗技术,是脑胶质瘤、黑色素瘤的极佳治疗手段,同时对复发性脖颈癌、肝转移癌等有良好的治疗响应.基于加速器的硼中子俘获治疗(AB-BNCT)具有靶向精确、副作用低、适应性广、体积较小、费用合理和一次性解决等优点.文章简要介绍了中国科学院高能物理研究所第二台BNCT加速器BNCT02的设计,详细说明了BNCT02 ECR离子源的设计、研制和调试.目前,在该离子源上已成功引出能量为35 keV,最大脉冲束流强度约40 mA及平均束流强度大于20 mA束流.低占空比小束流情况下,测得的束流的归一化均方根(rms)发射度小于0.2πmm·mrad.在离子源的稳定性测试中,也实现了在束流占空比80%、平均束流强度大于20 mA情况下的48 h稳定无故障运行.加速器的其他部件如射频四极加速器(RFQ)、RFQ功率耦合器、RFQ功率源、磁铁及其电源也都在研制中.

Boron Neutron Capture therapy(BNCT)is a safe and dual targeted radiotherapy technology,it offers a very satisfactory therapeutic effects for the treatment of malignant brain tumor and melanoma as well as a good response for the treatment of head-neck cancer,hepatic metastasis and so on.Accelerator-based boron neutron capture therapy(AB-BNCT)is of the advantage of precisely targeting,low side-effect,wide adaptability,small size,reasonable cost,and once for all,etc.In this paper,the designing of BNCT02 accelerator,which is the second accelerator dedicated to BNCT in our institute,is briefly introduced.Then,the designing,the manufacture and the commissioning of the ECR ion source for BNCT02 is presented in detail.At present,the beam with energy of 35 keV,a maximum pulse current of 40 mA and an average current larger than 20 mA is got from the ion source.The normalized rms emittance of the beam is measured smaller than 0.2πmm·mrad under conditions of small low duty factor and low current.The ion source has been running stably over 48 hours without any breakdown in the testwhen the beam duty cycle is 80%and the average beam intensity is greater than 20 mA.The other opponents of the accelerator such as the RFQ,RFQ power coupler,RFQ power source,magnets and their power supplier are also developed.