居家腹膜透析患者的药学延伸服务应用探索

Extended Pharmaceutical Care for Home Peritoneal Dialysis Patients

目的探讨药学延伸服务对居家腹膜透析患者的药物认知、药物疗效、用药依从性、生存质量及满意度的影响。方法选取2020年1月至2020年6月在陆军军医大学第二附属医院连续随访的86例居家腹膜透析患者,随机分为对照组和观察组。对照组提供常规药学服务,观察组提供药学延伸服务。通过电话随访、问卷调查等方法,比较两组患者药物认知、药物疗效、用药依从性、生存质量、患者满意度的差异。结果药学延伸服务干预后,观察组患者药物认知、用药依从性、生存质量、患者满意度平均得分分别为10.12.6.02.75.9630.57分,显著高于对照组患者对应项目平均得分6.43.3.80.47,16.6.18分(P<0.05);观察组患者血红蛋白水平平均值为110.48 g・L^(-1),较对照组平均值96.55 g・L^(-1)有显著提高(P<0.05);观察组患者收缩压与舒张压平均值分别为134.17.94.57 mmHg,较对照组对应平均值151.43,100.23 mmHg有显著提高(P<0.05)。结论药学延伸服务能在居家腹膜透析患者改善用药依从性、保障治疗效果、提高生存质量及满意度等方面起到积极作用,值得进一步探索并推广应用。

Objective To explore the effects of extended pharmaceutical care on amounts of knowledge of drugs,drug efficacy,medication compliance,quality of life and level of satisfaction among home peritoneal dialysis patients,and to provide reference for the pharmaceutical care of this type of patients.Methods A total of 86 patients on home peritoneal dialysis who were followed up continuously in the Second Affiliated Hospital of Army Medical University from January 2020 to June 2020 were randomly divided into the control group and observation group.The control group was provided with routine pharmaceutical care,while the observation group received extended pharmaceutical care.The amounts of knowledge of drugs,drug efficacy,medication compliance,quality of life and levels of satisfaction were compared between the two groups via phone calls and questionnaires.Results After the extended pharmaceutical care intervention,the average scores of amounts of knowledge of drugs,medication compliance,quality of life and patients'level of satisfaction in the observation group were 10.12,6.02,75.96 and 10.57,respectively,which were significantly higher than those in the control group(6.43,3.80,47.16 and 6.18,respectively).The average level of hemoglobin in the observation group was 110.48 g•L^(-1),which was significantly higher than 96.55 g•L^(-1)in the control group(P<0.05).The mean systolic and diastolic blood pressure in the observation group was 134.17 and 94.57 mmHg,respectively,significantly higher than 151.43 and 100.23 mmHg in the control group(P<0.05).Conclusion Extended pharmaceutical care can play a positive role in improving medication compliance,ensuring good therapeutic effect,improving quality of life and satisfaction of patients on home peritoneal dialysis,which should be made more accessible.