乳腺钼靶联合超声检查在早期乳腺癌筛查中的应用

Application of mammography combined with ultrasonography in early breast cancer screening

目的探讨乳腺钼靶联合超声检查在早期乳腺癌筛查中的应用价值。方法回顾性分析2018年8至2020年8月期间于韶关市仁化县妇幼保健院门诊就诊及妇女病普查中92例疑诊为早期乳腺癌的患者为研究对象,所有患者均接受穿刺病理检查及乳腺钼靶、超声检查,比较乳腺钼靶、超声等单项检查及联合检查对乳腺癌的诊断效能、不同检查方法对不同大小肿瘤的检出率。结果乳腺钼靶联合超声检查早期乳腺癌的灵敏度、特异度分别为90.00%、83.33%,明显高于乳腺钼靶检查的65.00%、50.00%和超声检查的53.75%、41.67%,差异均有统计学意义(P<0.05);在肿瘤直径<1.0 cm及1.0~1.5 cm时,超声检查及乳腺钼靶检查的检出率分别为36.00%和52.00%、40.74%和48.15%,明显低于联合检查的84.00%和85.19%,差异均有统计学意义(P<0.05);而肿瘤直径在1.6~2.0 cm及2.1~2.5 cm时,三种检查方法的检出率比较差异均无统计学意义(P>0.05)。结论乳腺钼靶及超声两种检查方法联合应用可提高早期乳腺癌检出率,具有较高的临床应用价值。

Objective To explore the application value of mammography combined with ultrasonography in the screening of early breast cancer.Methods Ninety-two patients suspected of early breast cancer in the Outpatient Clinic of Shaoguan Renhua Maternal and Child Health Hospital and the general survey of women's diseases from August 2018 to August 2020 were selected as the study subjects.All patients received biopsy,mammography,and ultrasonography.The diagnostic efficacy of mammography,ultrasonography alone,and mammography combined with ultrasonography were compared,and the detection rate of different size tumors by different examination methods was compared.Results The sensitivity,specificity of mammography combined with ultrasonography for early breast cancer were 90.00%,83.33%,respectively,which were significantly higher than 65.00%,50.00%of mammography and 53.75%,41.67%of ultrasonography(P<0.05).In tumor diameter<1.0 cm and of 1.0 cm to 1.5 cm,the detection rate of ultrasonography and mammography were 36.00%and 52.00%,40.74%and 48.15%,respectively,which were significantly lower than 84.00%and 85.19%of the combined examination(P<0.05).When the tumor diameter was 1.6-2.0 cm and 2.1-2.5 cm,there was no significant difference in the detection rate among the three methods(P>0.05).Conclusion The combined application of mammography and ultrasonography can improve the detection rate of early breast cancer,which has high clinical application value.