穴位贴敷联合瓜蒌薤白半夏汤对不稳定型心绞痛患者心功能的影响

Effects of Acupoint Application Combined with Gualou Xiebai Banxia Decoction on Cardiac Function in Patients with Unstable Angina Pectoris

目的:研究穴位贴敷联合瓜蒌薤白半夏汤对不稳定型心绞痛患者心功能的影响。方法:选取2019年9月至2020年9月河北以岭医院收治的不稳定型心绞痛患者116例作为研究对象,按照随机数字表法随机分为对照组和观察组,每组58例,对照组采用常规西药治疗,观察组在对照组的基础上采用穴位贴敷联合瓜蒌薤白半夏汤治疗,比较2组患者的临床疗效和治疗前后的中医证候积分、心功能、血脂指标、心绞痛发作情况等。结果:治疗后观察组总有效率为96.55%,显著高于对照组的77.59%(P<0.05);观察组中医证候积分、心绞痛发作次数及持续时间、硝酸甘油用量、左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)、总胆固醇(TC)、三酰甘油(TAG)、低密度脂蛋白胆固醇(LDL-C)水平均低于对照组(均P<0.05);治疗后观察组左室射血分数(LVEF)、高密度脂蛋白胆固醇(HDL-C)水平均显著高于对照组(均P<0.05)。结论:穴位贴敷联合瓜蒌薤白半夏汤治疗不稳定型心绞痛的疗效更好,能有效缓解临床症状,提高患者心功能,值得进一步的临床研究。

Objective:To study the effect of acupoint application combined with Gualou Xiebai Banxia Decoction on cardiac function in patients with unstable angina pectoris.Methods:A total of 116 patients with unstable angina pectoris admitted to Hebei Yiling Hospital from September 2019 to September 2020 were selected,and divided into two groups according to random number table method.The control group(58 cases)was treated with conventional western medicine,and the observation group(58 cases)was treated with acupoint application combined with Gualou Xiebai Banxia Decoction on the basis of control group.The clinical efficacy of the two groups and traditional Chinese medicine(TCM)symptom score,cardiac function,blood lipid index,and angina pectoris attack before and after treatment were compared.Results:After treatment,the total effective rate in the observation group was 96.55%higher than 77.59%in the control group.The TCM syndrome score,number and duration of angina pectoris attacks,dosage of nitroglycerin,left ventricular end-diastolic diameter(LVEDD),left ventricular systole end-systolic diameter(LVESD),total cholesterol(TC),triacylglycerol(TAG),and low-density lipoprotein cholesterol(LDL-C)level in the observation group were lower than those in the control group(all P<0.05),while the left ventricular ejection fraction(LVEF)in the observation group and high-density lipoprotein cholesterol(HDL-C)level were higher than those in the control group(all P<0.05).Conclusion:Acupoint application combined with Gualou Xiebai Banxia Decoction had desirable curative effect in the treatment of unstable angina pectoris,which relieved clinical symptoms and improved cardiac function of patients,and was worthy of further clinical research.