体质量管理对HFrEF患者心功能和生活质量的影响

Effects of Weight Management on Cardiac Function and Quality of Life in Patients With HFrEF

目的探讨体质量管理对慢性射血分数降低心力衰竭(heart failure with reduced ejection fraction,HFrEF)患者心功能和生活质量的影响。方法选择2018年8月—2020年8月增城区中医医院收治的150例HFrEF患者,按随机数字表法分为对照组和观察组,各75例。两组均给予基础药物治疗,对照组接受常规管理,观察组在对照组基础上增加体质量管理。对比两组患者的体质量、心功能、生活质量、1年内住院情况。结果干预后,观察组的体质量轻于对照组,差异有统计学意义(P<0.05)。观察组的血浆N末端B型利钠肽原(pro-B-type natriureticpeptide,NT-proBNP)水平低于对照组,左室射血分数(left ventricular ejection fraction,LVEF)高于对照组,6 min步行试验距离(6-min walking test,6 MWT)长于对照组,差异有统计学意义(P<0.05)。观察组的明尼苏达心功能不全生活质量(Minnesota living with heart failure questionnaire,MLHFQ)评分各领域及总分低于对照组,差异有统计学意义(P<0.05)。观察组在1年内住院>2次的机率低于对照组,差异有统计学意义(P<0.05)。结论通过强化体质量管理维持HFrEF患者的体质量稳定,可减轻水液潴留对心功能的影响,并降低再住院风险,改善患者的生活质量。

Objective To investigate the effects of weight management on cardiac function and quality of life in patients with chronic heart failure with reduced ejection fraction(HFrEF).Methods A total of 150 patients with HFrEF admitted to Zengcheng Hospital of Traditional Chinese Medicine from August 2018 to August 2020 were selected and divided into the control group and the observation group according to the random number table method,with 75 cases in each group.Both groups were given basic drug treatment,the control group was received routine management,and the observation group was received weight management on the basis of the control group.The body weight,cardiac function,quality of life,and hospitalization within 1 year were compared between the two groups.Results After the intervention,the weight of the observation group was lighter than that of the control group,the difference was statistically significant(P<0.05).The pro-B-type natriuretic peptide(NT-proBNP)level of the observation group was lower than that of the control group,the left ventricular ejection fraction(LVEF)was higher than that of the control group,and the 6-min walking test distance(6MWT)was longer than that of the control group,the differences were statistically significant(P<0.05).The Minnesota living with heart failure questionnaire(MLHFQ)scores in each field and total score in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).The probability of hospitalization for more than two times in one year in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion Maintaining a stable body weight in patients with HFrEF through intensive weight management can reduce the impact of fluid retention on cardiac function,reduce the risk of readmission,and improve the quality of life of patients.