超声造影在肝肿块穿刺活检中的应用价值

Application value of contrast-enhanced ultrasonography in liver mass biopsy

目的:探讨超声造影在肝肿块穿刺活检中的应用价值。方法:回顾性分析2019年1月至2021年12月在南通市肿瘤医院行肝肿块穿刺活检的190例患者(190枚肿物),其中行常规超声引导穿刺者118例(常规超声组),行超声造影引导穿刺者72例(超声造影组)。比较两组穿刺针显影情况、对坏死区和毗邻血管显示情况、穿刺次数及确诊率。结果:超声造影组对病灶坏死和毗邻大血管的显示率分别为33.33%、40.28%,显著高于常规超声的12.71%、23.73%(P<0.05)。超声造影组穿刺≤2次即获得较满意标本者占93.06%,显著高于常规超声组的75.42%,差异有统计学意义(P<0.05)。超声造影穿刺活检确诊率为95.83%,显著高于常规超声的89.83%,差异有统计学意义(P<0.05)。结论:相比常规超声,超声造影引导肝肿块穿刺可较好地显示坏死区和毗邻血管,有助于减少穿刺次数,提高穿刺确诊率。

Objective:To investigate the application value of contrast-enhanced ultrasound in liver mass biopsy.Methods:A retrospective analysis was performed on 190 patients(190 tumors)who underwent liver mass biopsy in Nantong Cancer Hospital from January 2019 to December 2021,including 118 cases of conventional ultrasound-guided biopsy(conventional ultrasound group)and 72 cases of contrast-enhanced ultrasound-guided biopsy(contrast-enhanced ultrasound group).The visualization of puncture needles,the display of necrotic area and adjacent blood vessels,the number of punctures,and diagnosis rate were compared between the 2 groups.Results:The display rates of necrosis and adjacent large vessels in contrast-enhanced ultrasound group were 33.33%and 40.28%,respectively,which were significantly higher than 12.71%and 23.73%in the conventional ultrasound(P<0.05).In the contrast-enhanced ultrasound group,93.06%of patients obtained satisfactory specimens when punctured less than or equal to 2 times,which was significantly higher than 75.42%in the conventional ultrasound group,and the difference was statistically significant(P<0.05).The diagnostic rate of CEUS puncture biopsy was 95.83%,which was significantly higher than that of conventional ultrasound(89.83%),and the difference was statistically significant(P<0.05).Conclusion:Compared with conventional ultrasound,contrast-enhanced ultrasound-guided liver mass puncture can better display necrotic areas and adjacent blood vessels,which helps to reduce the number of punctures and improve the diagnostic rate of puncture.