TFE-EPI序列与TFE序列在3.0 T非增强冠状动脉MR血管成像中的对比研究

An investigation of comparison between TFE-EPI and TFE in non-enhanced coronary MR angiography on 3.0 T MRI

目的探讨3.0 T MRI使用单次屏气快速场回波平面回波成像(TFE-EPI)序列行非增强冠状动脉MRA(CMRA)的可行性。方法2021年10月前瞻性入组23名健康志愿者,分别采集单次屏气TFE-EPI序列和自由呼吸快速场回波(TFE)序列非增强CMRA。使用配对样本t检验比较两组的采集时间。使用Wilcoxon非参数检验分析评价两组不同部位血管的信噪比(SNR)、对比噪声比(CNR)、图像伪影及变形、血管锐利度。评价血管包括主动脉、右冠状动脉近端、右冠状动脉中段、左前降支近段和左回旋支近段。结果单次屏气TFE-EPI序列的采集时间[(16.3±2.2)s]比自由呼吸TFE序列[(466.9±101.3)s]缩短了96.51%,差异有统计学意义(t=21.49,P<0.01)。两者各部位血管的SNR差异均无统计学意义(P均>0.05)。TFE-EPI序列在右冠状动脉中段CNR明显优于TFE序列(Z=2.65,P=0.008)。在图像伪影及变形的比较中,TFE-EPI序列在右冠状动脉中段优于TFE序列(Z=2.00,P=0.046)。在血管锐利度的比较中,TFE-EPI序列在右冠状动脉近段和中段优于TFE序列(Z=3.88,P<0.001;Z=3.42,P=0.001)。结论单次屏气TFE-EPI序列可以在保证图像质量的情况下大幅缩短采集时间,在非增强CMRA成像中有着广泛的应用前景。

Objective To investigate the feasibility of single breath-hold TFE-EPI in non-contrast coronary MRA on 3.0 T MRI.Methods Both single breath-hold TFE-EPI and free breathing TFE were conducted in 23 healthy volunteers.Acquisition time between the two sequences were compared by paired-t-test analysis.Signal-noise-ratio(SNR),contrast-noise-ratio(CNR),image artifacts and distortion,vessel acuity were evaluated on the aorta(Ao),right coronary artery proximal(RCA-pro),right coronary artery middle(RCA-mid),left anterior descending proximal(LAD-pro)and left circumflex proximal(LCX-pro).Nonparametric analyses were conducted for the comparison.Results The acquisition time decreased 96.51%in TFE-EPI compared with TFE[(16.3±2.2)s vs.(466.9±101.3)s,t=21.49,P<0.01].There was no statistical significance in SNR comparison in all the vessel evaluation(all the P>0.05).TFE-EPI showed better CNR in RCA-mid than TFE(Z=2.65,P=0.008).TFE-EPI showed less image artifacts and distortion in RCA-mid than TFE(Z=2.00,P=0.046).TFE-EPI also showed better vessel acuity in both RCA-pro and RCA-mid than TFE(Z=3.88,P<0.001;Z=3.42,P=0.001).Conclusion Single breath-hold TFE-EPI could greatly shorten scan time while ensuring image quality in coronal artery imaging and has a broad application in future.