新型冠状病毒肺炎儿童合并急性脑炎的临床特点及研究进展

Clinical features of children with coronavirus disease 2019 complicated by acute encephalitis and related research advances

2019年底以来,新型冠状病毒肺炎(coronavirus disease 2019,COVID-19)在世界范围内大流行,该病出现神经系统症状的报道不断增加。其中,脑炎被认为是COVID-19严重的神经系统并发症,但国内报道缺乏。合并急性脑炎患儿症状重,如未能早期识别、及时治疗,病死率高,预后差。目前全球疫情仍在流行期间,有必要对COVID-19儿童神经系统重症表现予以关注。因此该综述通过文献检索及详细病案分析,探讨COVID-19合并急性脑炎的临床特点,旨在为临床医生应对可能出现的COVID-19合并急性脑炎病例提供参考。

Coronavirus disease 2019(COVID-19)has become a worldwide pandemic since the end of 2019.There is an increasing number of reports on nervous system symptoms,among which encephalitis is considered a serious neurological complication of COVID-19,but there are few reports of this complication in China.Acute encephalitis has severe symptoms.If it is not identified early and treated in time,the mortality is high and the prognosis is poor.During the current global epidemic,it is necessary to pay attention to the severe nervous system symptoms of COVID-19.Therefore,this article summarizes the clinical features of COVID-19 complicated by acute encephalitis through literature review and a detailed analysis of medical records,so as to provide a reference for clinicians to deal with the cases of COVID-19 complicated by acute encephalitis.