摘要
肠道菌群与人体的健康密切相关,人体为肠道菌群的生长、发育和繁殖提供了稳定的环境,同时肠道菌群也影响着人体的代谢。近年来,随着研究的深入,肠道菌群影响人体代谢的多种途径不断被发现,其中肠道菌群的代谢产物——短链脂肪酸(SCFAs)起着至关重要的作用。短链脂肪酸(SCFAs)可以影响不同组织和器官的生理功能从而调控全身代谢,并且在一些代谢性疾病的治疗上具有广阔的前景。
Growing evidence has revealeda strong association of the gut microbiotawithmetabolic diseases of human beings.Literature has recently proposed an important role for the key metabolites deriving from the gut microbiota,namely short chain fatty acids(SCFAs),to maintain host's metabolic homeostasis.SCFAs regulate systemic metabolism by affecting physiology of different tissues and organs.Moreover,it can be use as therapies for some metabolic diseases with broad prospects.In this Review,we discuss the current findings on how SCFAs contribute to the metabolic health of host.
作者
谭肖卓
曹冲
邵怡凯
姚琪远
Tan XiaoZhuo;Cao Chong;Shao YiKai;Yao QiYuan(Department of General Surgery,Huashan Hospital,Fudan University,Shanghai 200040,China)
出处
《中华肥胖与代谢病电子杂志》
2022年第1期46-51,共6页
Chinese Journal Of Obesity and Metabolic Diseases:Electronic Edition
基金
国家自然科学基金(81970458)。
关键词
肠道菌群
短链脂肪酸
代谢性疾病
肥胖
Gut microbiota
Short-chain fatty acids(SCFAs)
Metabolic diseases
Obesity