肝泡型包虫病浸润带及其微血管侵犯的研究进展

Research progress on infiltrating zone and microvascular invasion of hepatic alveolar echinococcosis

肝泡型包虫病是一种生物学特性类似恶性肿瘤的寄生虫疾病, 早期无明显临床症状, 多数患者就诊时已出现黄疸、腹水及消化道出血等并发症, 此时病程已属晚期。此外, 由于病灶切除的不彻底导致术后较高的复发率, 给患者的身心健康带来了严重的影响。本文通过对国内外最新研究的总结, 以及对肝泡型包虫病病灶旁"浸润带"内血供、微血管侵犯及血管生长因子表达情况的分析, 深度了解肝泡型包虫病的发生发展过程, 旨在更好地指导临床实践和提高患者的生存质量。

Hepatic alveolar echinococcosis(AE)is a parasitic disease with biological characteristics similar to malignant tumor.It has no obvious clinical symptoms in the early stage.Most patients have complications such as jaundice,ascites and gastrointestinal bleeding when they see a doctor.At this time,the course of disease is at an advanced stage.In addition,the incomplete resection of the AE lesion(s)leads to a high postoperative recurrence rate,which has a serious impact on the physical and mental health of patients.Based on the summary of the latest research at home and abroad and the analysis of blood supply,microvascular invasion and vascular growth factor expression in the"infiltrating zone"adjacent to the lesions of hepatic AE,this article has a deep understanding of the occurrence and development process of hepatic AE,aiming to better guide clinical practice and improve the quality of life of patients.