脑电图分级标准在急性大面积缺血性脑卒中患者预后评估中的临床研究

Clinical study of EEG grading standard in the prognostic evaluation of patients with acute massive ischemic stroke

目的探讨脑电图(electroencephalogram,EEG)分级标准在急性大面积缺血性脑卒中患者脑功能损伤评价及预后评估中的作用。方法收集2016年7月-2020年7月首都医科大学附属复兴医院神经内科收治的发病5 d内的68例急性大面积缺血性脑卒中患者脑电图进行EEG分级判定,记录并使用格拉斯哥昏迷评分(glasgow coma scale,GCS)、美国国立卫生研究院卒中量表(NIH stroke scale,NIHSS)评分,随访至90 d进行格拉斯哥预后评分(glasgow outcome scale,GOS),并采用Logistic回归分析评估各项评分系统的预测价值。结果本组患者的EEG分级标准与预后有显著相关性(P<0.01),EEG分级评分越高,患者的神经功能预后越差。Logistic回归分析显示EEG分级标准的转归良好及不良预测准确率、综合预测准确率最高。结论脑电图分级标准在急性大面积缺血性脑卒中患者预后研究中能更客观地反映脑功能损伤的程度,可以作为发病早期预后评估的预测指标。

Objective The aim of this study was to explore the role of electroencephalogram grading standard for brain function damage and prognosis in patients with acute massive ischemic stroke(AMIS).Methods The samples comprised 68 patients from Fu Xing Hospital affiliated to Capital Medical University.EEG were collected and EEG classification were recorded.Also National Institute of Health stroke score(NIHSS)and GCS/NIHSS score were recorded.And GOS score were analysed at 3 months after onset.Results EEG grading standard exhibited much closer correlation with outcome(P<0.01):the higher the EEG grade was,the poorer the outcome was.Logistic regression analysis showed that the good and bad prognosis and comprehensive prediction of EEG grading standard was the highest.Conclusions EEG grading standard can reflect the degree of brain function damage more objectively in the study of prognosis of patients with acute massive ischemic stroke,and can be used as a predictor of early prognosis evaluation.