2012—2021年国家自然科学基金脑卒中中医内科研究领域申请与资助分析——基于CiteSpace的可视化分析

Visualization analysis of the application and funding of the NSFC in the field of TCM research on stroke from 2012 to 2021 based on CiteSpace

目的对2012—2021年国家自然科学基金中风病中医内科(H3108)领域的申请与资助情况、研究热点及存在问题分析,以期为本领域研究人员宏观把握中风病中医药研究的整体动向及后续研究提供思路与方法参考。方法采用Citespace软件对申请及资助项目关键词知识图谱可视化分析。结果2012—2021年中医内科脑卒中研究共申请项目567项,资助面上项目、青年科学基金项目和地区科学基金项目共83项,资助金额总计4160万元。缺血性中风研究以“外泌体”“自噬”“肠道菌群”“氧化应激”“炎症”“血管新生”“神经保护”等热点为主。出血性中风研究热点聚焦在“血脑屏障”“脑水肿”“铁死亡”“自噬”“胶质细胞”“细胞凋亡”“时间窗”等方面。结论10年来,国家自然科学基金对中风病中医药研究领域的持续稳定资助,在促进学科发展、人才的培养等方面都有较好的支撑,但同时也存在支持力度相对不足、研究学术集群明显、项目选题分布相对单一、“套路化”研究模式现象突出等问题。建议中风病中医药研究要立足遵循学科发展与学术研究的内在逻辑,主动追踪并积极介入国家战略与重大需求,以临床价值和彰显中医药的特色和优势为导向,理性把握研究范围,应用现代多学科交叉研究手段,推动中风病中医药研究高质量发展。

Objective To analyze the application and funding,research hotspots and existing problems in the field of TCM internal medicine for stroke(H3108)under the National Natural Science Foundation of China from 2012 to 2021,so as to provide ideas and methods for researchers in this field to grasp the overall trend of TCM research on stroke and the follow-up research.Methods The Citespace software was used to conduct a visualization analysis on the keyword knowledge map of the applied and funded projects.Results From 2012 to 2021,a total of 567 projects were applied for the stroke research in internal medicine of traditional Chinese medicine,and 83 projects were funded by the general National Natural Science Foundation,the National Natural Science Foundation for Distinguished Young Scholars and the regional science foundations,with a total funding of 41.6 million yuan.Studies on ischemic stroke mainly focus on"exosomes","autophagy","intestinal flora","oxidative stress","inflammation","angiogenesis","neuroprotection"and other hotspots,while studies on hemorrhagic stroke mainly focus on"blood-brain barrier","cerebral edema","iron death","autophagy","glial cells","apoptosis","time window"and other aspects.Conclusion In the past 10 years,the NSFC’s continuous and stable support in the field of the traditional Chinese medicine research on stroke has provided a good support in promoting the discipline development and talent training,but there are also problems such as a relatively insufficient support,obvious academic clusters,a relatively homogeneous distribution of project topics,and a prominent"routine"research mode.It is suggested that the TCM research on stroke should be based on the inherent logic of discipline development and academic research,actively track and engage in the national strategies and significant requirements,take the clinical value and highlighting the characteristics and advantages of TCM as the guidance,rationally grasp the research scope,apply the modern interdisciplinary research methods,and promote the high-quality development of TCM research on stroke.