肺炎链球菌感染研究进展

Research advances of Streptococcus pneumoniae infection

肺炎链球菌(S.pn)作为细菌性肺炎、中耳炎、脑膜炎和败血症的主要病原体,其感染一直以来是全球不可忽视的健康问题。近年来,肺炎链球菌毒力和耐药性的不断增强,对公共健康的威胁越来越大。PCR和基因测序等基因组领域新的实验室诊断方法逐渐受到重视,本文旨在通过对肺炎链球菌的病原学、黏附和侵袭方式、毒力因子以及现有实验室诊断方法和防治手段进行分析,从而为深入理解肺炎链球菌以及寻找有效的防治措施提供参考。

Streptococcus pneumoniae(S.pn),as the major pathogen of bacterial pneumonia,otitis media,meningitis and septicemia,its infection has always been a global health problem that cannot be ignored.In recent years,the growing virulence and resistance of Streptococcus pneumoniae has posed an increasing threat to public health.New laboratory diagnostic approaches in the genomic field such as PCR and gene sequencing are gradually gaining attention.This article aims to provide reference for in-depth understanding of Streptococcus pneumoniae and seeking effective prevention and treatment measures by analyzing the etiology,adhesion and invasion modes,virulence factors,and existing laboratory diagnosis and prevention methods of Streptococcus pneumoniae.