摘要
高尔基磷酸化蛋白3(golgi phosphoprotein 3,GOLPH3)具有典型的高尔基体结构,发挥着维持高尔基体正常形态结构和生理功能的重要作用。在多种肿瘤的研究中,GOLPH3均被证明呈高表达状态,与肿瘤的发生和转移密切相关。近年来随着研究的不断深入,成为肿瘤诊治的重要靶点,因此文章对高尔基磷酸化蛋白3在肿瘤中的研究进展进行综述。
Golgi phosphoprotein 3(GOLPH3)has a typical Golgi structure and plays an important role in maintaining normal morphological structure and physiological function of Golgi.GOLPH3 has been shown to be highly expressed in a variety of tumors.It is also closely related to tumor occurrence and metastasis.Based on recent research advances,GOLPH3 has become an important target for tumor diagnosis and treatment.This report reviews the research progress of GOLPH3 in tumors.
作者
韦自卫
王忠
李文智
Wei Ziwei;Wang Zhong;Li Wenzhi(Department of Urology,Shanghai Ninth People’s Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200011,China;Department of Urology,Jinshan Hospital,Fudan University,Shanghai 201508,China)
出处
《泌尿外科杂志（电子版）》
2022年第2期69-73,共5页
Journal of Urology for Clinicians(Electronic Version)
基金
上海市自然科学基金面上项目(20ZR1431400)。
