摘要
目的为临床药师参与异基因造血干细胞移植后感染患者临床药学实践提供思路。方法临床药师全程参与1例异基因造血干细胞移植后患儿诊疗经过,住院期间先后出现耐药巨细胞病毒重症肺炎、耐碳青霉烯鲍曼不动杆菌重症肺炎,临床药师通过查阅文献,建议调整抗耐药巨细胞病毒方案和耐碳青霉烯鲍曼不动杆菌治疗方案,并对临床疗效、多种抗感染药物相互作用和药品不良反应进行监护。结果根据患儿病情变化及时调整药物治疗方案,使其顺利度过危险期,未发生常见不良反应。结论临床药师积极参与药学监护,能协助医生及时制定、调整药物治疗方案,提高治疗效果,减少药品不良反应发生。
OBJECTIVE To share experimences for clinical pharmacists to participate in pharmaceutical practice of severe pneumonia patients by allogeneic hematopoietic stem cell transplanted.METHODS During hospitalization,the patients were identified severe pneumonia caused by drug-resistant cytomegalovirus and carbapenem-resistant Acinetobacter baumannii.Clinical pharmacists participated in clinical multidisciplinary team and played an important role in it.RESULTS The patient was improved to be stable.CONCLUSION Clinical pharmacists actively participate in pharmaceutical care,which would support doctors to adjust effective plan in time,improve treatment effect and reduce adverse drug reactions.
作者
林彩琴
钟文
周密
LIN Cai-qin;ZHONG Wen;ZHOU Mi(Department of Pharmacy,The First People′s Hospital of Hechi,Hechi 546300,China;Department of Pharmacy,Children′s Hospital of Soochow University,Suzhou 215000,China)
出处
《海峡药学》
2022年第10期72-76,共5页
Strait Pharmaceutical Journal
基金
苏州市科技局项目(SYSD2018240)。
关键词
异基因造血干细胞移植
巨细胞病毒
耐碳青霉烯鲍曼不动杆菌
重症肺炎
药学监护
Allogeneic hematopoietic stem cell transplantation
Cytomegalovirus
Carbapenem-resistant Acinetobacter baumannii
Severe pneumonia
Pharmaceutical care
