依达拉奉氯化钠注射液联合电脑中频电治疗急性脑梗死的效果观察

Effect Observation of Edaravone Sodium Chloride Injection Combined with Computer Intermediate Frequency Electrotherapy in Treatment of Acute Cerebral Infarction

目的探讨急性脑梗死(ACI)患者采用依达拉奉氯化钠注射液联合电脑中频电治疗的临床效果。方法选取2019年1月-2022年7月在萍乡市人民医院治疗的ACI患者共计60例,按照随机数字表法分成观察组(30例)和对照组(30例)。对照组给予电脑中频电治疗,观察组给予依达拉奉氯化钠注射液联合电脑中频电治疗,比较两组临床疗效、神经功能、日常生活能力及经颅多普勒超声(TCD)检查结果。结果观察组治疗总有效率高于对照组(P<0.05);两组治疗后美国国立卫生研究院卒中量表(NIHSS)、改良Rankin量表(mRS)评分低于治疗前,欧洲神经功能缺损评分量表(ESS)高于治疗前,且观察组NIHSS、mRS评分低于对照组,ESS高于对照组(P<0.05);两组治疗后改良Barthel指数(MBI)评分高于治疗前,且观察组高于对照组(P<0.05);两组治疗后大脑前(ACA)、中(MCA)、后(PCA)动脉指数低于治疗前,观察组低于对照组(P<0.05)。结论ACI患者采用依达拉奉氯化钠注射液与电脑中频电联合治疗的临床疗效较高,可有效改善神经功能、日常生活能力。

Objective To investigate the clinical effect of edaravone sodium chloride injection combined with computer intermediate frequency electric therapy in patients with acute cerebral infarction(ACI).Methods A total of 60 ACI patients treated in Pingxiang People's Hospital from January 2019 to July 2022 were selected and divided into observation group(30 cases)and control group(30 cases)according to the random number table method.The control group was treated with computer intermediate frequency electrotherapy,and the observation group was treated with edaravone sodium chloride injection combined with computer intermediate frequency electrotherapy.The clinical efficacy,neurological function,daily living ability and transcranial Doppler ultrasound(TCD)results were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the National Institutes of Health Stroke Scale(NIHSS)and modified Rankin Scale(mRS)scores of the two groups were lower than those before treatment,and the European Neurological Deficit Scale(ESS)was higher than that before treatment,while the NIHSS and mRS scores of the observation group were lower than those of the control group,and the ESS was higher than that of the control group(P<0.05).The modified Barthel index(MBI)scores of the two groups after treatment were higher than those before treatment,and the observation group was higher than the control group(P<0.05),while the anterior cerebral artery(ACA),middle cerebral artery(MCA)and posterior cerebral artery(PCA)indexes of the two groups after treatment were lower than those before treatment,and the observation group was lower than the control group(P<0.05).Conclusion The clinical efficacy of edaravone sodium chloride injection combined with computer intermediate frequency electric therapy in patients with ACI is high,which can effectively improve neurological function,activities of daily living.