改进型耳部清洗受水器在行冲洗治疗的慢性化脓性中耳炎患者中的应用效果

Effect of Improved Ear Washout Receiver on Irrigation Treatment of Patients with Chronic Suppurative Otitis Media

目的探讨改进型耳部清洗受水器在行冲洗治疗的慢性化脓性中耳炎患者中的应用效果。方法选取2020年3月至2021年10月联勤保障部队第九一〇医院耳鼻喉科收治的114例慢性化脓性中耳炎患者为研究对象,将其随机分为对照组与试验组,各57例。两组均行冲洗治疗,对照组使用常规耳部清洗受水器进行冲洗,试验组使用改进型耳部清洗受水器进行冲洗,比较两组症状改善时间、住院时间,治疗后临床疗效,治疗前后中耳积液炎症因子[包括转化生长因子-β_(1)(TGF-β_(1))、白细胞介素-8(IL-8)及白细胞介素-1β(IL-1β)]水平以及听力障碍程度[采用听力障碍量表(HHI)评估]、咽鼓管功能障碍程度[采用咽鼓管功能障碍7项问卷(ETDQ-7)评估]、患耳气骨导差值的统计学差异。结果试验组耳痛、耳闷、耳鸣、流脓改善时间及住院时间均短于对照组,差异有统计学意义(P<0.05)。治疗后30 d,两组临床疗效比较,差异有统计学意义(P<0.05);两组总有效率比较,差异无统计学意义(P>0.05);两组中耳积液TGF-β_(1)、IL-8、IL-1β水平及HHI、ETDQ-7评分、患耳气骨导差值均低于治疗前,且试验组均低于对照组,差异有统计学意义(P<0.05)。结论改进型耳部清洗受水器在行冲洗治疗的慢性化脓性中耳炎患者中的应用效果确切,可有效减轻患者听力障碍程度与炎症状态。

Objective To investigate the effect of using improved ear cleaning and receiving device in the treatment of chronic suppurative otitis media.Methods From March 2020 to October 2021,114 patients with chronic suppurative otitis media in the Otolaryngology Department of 910 Hospital of Joint Logistic Support Force were randomly divided into control group and experimental group,with 57 patients in each group.The control group was irrigated with conventional ear cleaning and receiving device,while the experimental group was irrigated with improved ear cleaning and receiving device.The symptom improvement time,hospital stay,and clinical efficacy after treatment were compared between the two groups.The levels of inflammatory factors in middle ear effusion[including TGF-β_(1),IL-8,and IL-1β],the degree of hearing impairment(assessed by the Hearing Impairment Scale(HHI)),the degree of Eustachian tube dysfunction(assessed by the 7-items Eustachian Tube Dysfunction Questionnaire(ETDQ-7)),and the air-bone conduction difference of the affected ear before and after treatment were statistically different.Result The improvement time of earache,ear tightness,tinnitus,pus discharge and hospital stay in the experimental group were shorter than those in the control group(P<0.05).30 days after treatment,the clinical efficacy of the two groups was compared,and the difference was statistically significant(P<0.05).There was no significant difference in the total effective rate between the two groups(P>0.05).The levels of TGF-β_(1),IL-8 and IL-1βin middle ear effusion,HHI and ETDQ-7 scores,and the air-bone conductances of affected ear in the two groups were lower than those before treatment,and the experimental group was lower than the control group,and the differences were statistically significant(P<0.05).Conclusion The application of improved ear cleaning water receiver in the treatment of chronic suppurative otitis media is effective,which can effectively reduce the degree of hearing impairment and inflammation of patients.