替加环素治疗1例小儿耐药支原体合并多重耐药鲍曼不动杆菌感染的分析

Analysis of Tigecycline in Treatment of a Child with Multidrug-resistant Mycoplasma and Acinetobacter baumannii Infection

临床药师通过查阅文献寻找证据,分析替加环素用于小儿耐药支原体合并多重耐药鲍曼不动杆菌(MDRAB)感染的安全性和有效性,为1例该混合病原菌感染的患儿提供治疗决策,并实施药学监护,患儿最终取得了良好的疗效,且未发生替加环素相关不良反应。临床药师可在小儿超说明书用药方面发挥重要作用,为儿童安全用药保驾护航。

The clinical pharmacists reviewed the literature for evidence,and analyzing the safety and effectiveness of tigecycline for multidrug-resistant Acinetobacter baumannii(MDRAB) infection in children with drug-resistant mycoplasma.Then cooperated with clinicians to make treatment decisions and implement pharmaceutical care for a child infected with this mixed pathogen.The patient achieved a good outcome and had no adverse reactions related to tigecycline.Clinical pharmacists can play an important role in off-label drug use in children and escort children’s safe drug use.