新型敷料治疗糖尿病足感染的疗效及对血清相关指标的影响

Efficacy of Therapy with New Dressing in Diabetic Foot Infection and Its Influence on Serum Related Index

目的:分析藻酸盐银离子敷料治疗糖尿病足感染的疗效及对血清相关指标的影响。方法:选取2021年1月—10月我院收治的80例糖尿病足感染患者,采用随机数字表法分为对照组(40例)和观察组(40例)。对照组采用凡士林敷料,观察组采用藻酸盐银离子敷料。比较两组患者愈合时间、换药情况、创面面积与症状评分、血清指标水平及临床疗效。结果:观察组创面愈合时间、换药次数明显低于对照组(P<0.05),治疗总有效率明显高于对照组(P<0.05);两组患者治疗后2周、4周创面面积、创面症状评分、白细胞介素-6(IL-6)及红细胞沉降率(ESR)水平明显低于治疗前(P<0.05),治疗后4周明显低于治疗后2周(P<0.05),且观察组明显低于对照组(P<0.05)。结论:相较于凡士林敷料,采用藻酸盐银离子敷料治疗糖尿病足感染疗效更好,可有效促进创面愈合,缓解创面症状,减少创面面积及换药次数,控制机体炎症反应。

Objective To analyze the efficacy of the therapy with silver alginate ion dressing in diabetic foot infection and its influence on serum related index.Methods 80 patients with diabetic foot infection admitted to our hospital from January 2021 to October 2021 were selected and divided into control group(40 cases)and observation group(40 cases)by random number table method.Vaseline dressing was used in the control group and silver alginate ion dressing was used in the observation group.The healing time,dressing change,wound area,symptom score,the level of serum index and clinical efficacy of both groups were compared.Results The wound healing time and dressing change times of the observation group were obviously lower in comparison with those of the control group(P<0.05),and the therapy total effective rate was obviously higher in comparison with that of the control group(P<0.05).The wound area,wound symptom score,the levels of interleukin-6(IL-6)and erythrocyte sedimentation rate(ESR)in 2 and 4 weeks after therapy of both groups were obviously lower in comparison with those before therapy(P<0.05),4 weeks after therapy were obviously lower in comparison with those 2 weeks after therapy(P<0.05),and the observation group were obviously lower in comparison with those in the control group(P<0.05).Conclusion Compared with vaseline dressing,the efficacy of the therapy with silver alginate ion dressing in diabetic foot infection was better,which can effectively promote the wound healing,relieve the wound symptom,reduce the wound area and dressing change times,as well as control the inflammatory response of body.