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内镜下黏膜剥离术治疗早期胃癌155例效果 被引量:3

Efficacy in 155 cases with endoscopic submucosal dissection for early gastric cancer
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摘要 目的对在基层医院实施内镜下黏膜剥离术(ESD)治疗早期胃癌的效果进行评价。方法对安庆市第一人民医院2018年12月至2021年6月收治的155例行ESD治疗的早期胃癌患者临床资料作回顾性总结,分析ESD治疗早期胃癌的效果和安全性。结果155例早期胃癌患者,病灶大小为(1.55±0.38)cm,手术时间为(59.20±14.83)min,患者住院时间为(5.00±1.21)d。13例因癌组织浸润深度超过黏膜下层的500μm转外科追加手术。发生早期出血2例,延迟性出血5例,贲门部狭窄3例,幽门狭窄1例,无穿孔发生,并发症发生率为7.10%(11/155)。随访6个月时内镜复查,创面愈合率为100%。随访1年,局部复发率为0。结论ESD治疗早期胃癌具有恢复快、并发症少、住院时间短的优点,适合基层医院开展。 Objective To evaluate the effect of endoscopic mucosal dissection(ESD)in the treatment of early gastric cancer.Methods A retrospective analysis was performed on the clinical data of 155 patients with early gastric cancer who underwent ESD in Anqing First People's Hospital from December 2018 to June 2021 to evaluate the efficacy and safety of ESD for early gastric cancer.Results Among 155 cases,the mean lesion size was(1.55±0.38)cm,the operation time was(59.20±14.83)min,and the hospital stay was(5.00±1.21)d.The additional surgery was conducted in 13 cases because of the depth of invasion of cancer tissue being more than 500μm in the submucosa.There were 2 cases of early bleeding,5 cases of delayed bleeding,3 cases of cardio stenosis,1 case of pyloric stenosis and no perforation occurring.The complication rate was 7.10%(11/155).Endoscopic reexamination suggested the wound healing rate was 100%at 6 months after operation.The local recurrence rate was 0 during 1 year follow-up.Conclusion In the treatment of early gastric cancer,ESD has the advantages of rapid recovery,fewer complications and short hospitalization time and is also suitable for grass-roots hospitals.
作者 余芳芳 刘朝旭 凌安生 YU Fang-fang;LIU Chao-xu;LING An-sheng(Department of Gastroenterology,Anqing First People's Hospital,Anqing,Anhui 246004,China;不详)
出处 《中国临床研究》 CAS 2022年第11期1544-1546,1550,共4页 Chinese Journal of Clinical Research
基金 国家自然科学基金(81670587)。
关键词 胃癌 早期 内镜下黏膜剥离术 出血 穿孔 Gastric cancer,early Endoscopic submucosal dissection Bleeding Perforation
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