进展期结直肠腺瘤危险因素及预防的研究进展

Research progress of risk factors and prevention of advanced colorectal adenomas

随着人们生活水平的提高,结直肠癌发病率呈逐年上升趋势。进展期结直肠腺瘤(ACA)为结直肠癌的重要癌前病变,但国内关于ACA的发病危险因素及有效预防措施研究有限,因此深入研究ACA是临床所必须和迫切需要的。目前导致ACA的主要危险因素有年龄、性别、饮食、肥胖、结肠癌家族史、合并结肠黑变病等,本文将对ACA危险因素及预防方面的研究进展作一综述,有助于降低结直肠癌的发生率和延缓ACA的进展。

With the improvement of people's living standards,the incidence of colorectal cancer(CRC)is increasing year by year.Advanced colorectal adenoma(ACA)is an important precancerous lesion of CRC,but there is limited domestic research on the risk factors and effective prevention measures,so it is necessary and urgent to make a profound study of ACA.At present,the main risk factors of ACA include age,sex,diet,obesity,family history of colon cancer and melanosis coli.This review will summarize the research progress in risk factors and prevention of ACA,which will help to reduce the incidence of CRC and delay the progress of ACA.