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老年脑出血术后轻度认知功能障碍现状调查及转归 被引量:3

Investigation of the current status and prognosis of mild cognitive impairment in elderly patients after cerebral hemorrhage surgery
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摘要 目的调查老年脑出血患者术后轻度认知功能障碍(MCI)现状及转归,为临床干预提供参考。方法选取2017年1月至2021年10月于空军军医大学第一附属医院脑出血术后MCI患者386例为研究对象。采用自行设计的流行病学调查表进行调查,每位患者均接受神经心理学测验,采用智力测试反映认知功能的变化趋势,以老年痴呆为随访结局,研究MCI患者转归流行病学。结果年龄越大、女性、文化程度越低、体力劳动者、单身、家庭月收入<500元的MCI患者MMSE评分更低(P<0.01)。Logistic回归分析显示,年龄(OR=1.968,P=0.037)、性别(OR=1.863,P=0.044)、文化程度(OR=0.550,P=0.039)和月收入(OR=1.866,P=0.031)为脑出血术后发生MCI的独立影响因素。MCI患者认知减退率12.95%,认知恢复率5.51%,痴呆率3.03%。年龄越大、女性、文化程度越低、体力劳动者、单身、家庭月收入<500元的患者认知减退甚至进展为痴呆的比例更高(P<0.05)。结论对MCI患者进行现状调查和转归流行病学研究,有利于有效预警早期痴呆状态,便于及时干预。 Objective To investigate and study the current status of mild cognitive impairment(MCI)and epidemiological study of prognosis in elderly patients after cerebral hemorrhage surgery.Methods A total of 386 patients received cerebral hemorrhage surgery in the First Affiliated Hospital of Air Force Military Medical University were enrolled as the research objects between January 2017 and October 2021.All patients were investigated by self-designed epidemiological questionnaires and were given neuropsychological tests.During follow-up,change trends of cognitive function were reflected by intelligence tests.Taking senile dementia as the follow-up outcomes,prognosis epidemiology of MCI patients was studied.Results The cognitive function of MCI patients was lower in those with older age,female gender,lower educational level,physical labour,single person state and family monthly income<500 yuan(OR=1.866,P<0.05).Age(OR=1.968,P=0.037),gender(OR=1.863,P=0.044),educational level(OR=0.550,P=0.039)and monthly income(OR=1.866,P=0.031)were independent influencing factors of MCI after cerebral hemorrhage surgery.The incidence rates of cognitive decline,cognitive recovery and dementia in MCI patients were 12.95%,5.51%and 3.03%,respectively.The incidence of cognitive decline or even progress to dementia was higher in patients with older age,female gender,lower educational level,physical labor,single person state and family monthly income<500 yuan.Conclusion The investigation of current status and epidemiological study of prognosis are conducive to effective early warning of dementia and timely intervention in MCI patients.
作者 薛方方 潘金凤 叶玉勤 XUE Fang-fang;PAN Jin-feng;YE Yu-qin(Neurosurgery Operating Room,the First Affiliated Hospital of Air Force Military Medical University,Xi'an,Shaanxi 723000,China)
出处 《中国临床研究》 CAS 2022年第11期1614-1618,共5页 Chinese Journal of Clinical Research
基金 陕西省自然科学基金(2022JM-437)。
关键词 脑出血 轻度认知功能障碍 痴呆 康复护理 认知减退 Cerebral hemorrhage Mild cognitive impairment Dementia Rehabilitation nursing Cognitive decline
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