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彝族药紫地榆的研究进展及其质量标志物预测分析

Research progress in Yi medicine Geranium strictipes Knuth and predictive analysis of quality markers
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摘要 紫地榆(Geranium strictipes Knuth)为云南省特有的民族药,其药用历史悠久,常用于治疗便血、痔血、血痢、崩漏、水火烫伤、痈肿疮毒等,在彝族应用广泛。在对紫地榆化学成分、药理作用研究论述的基础上,从原植物亲缘学及化学成分特有性、传统功效及药性、新的药效用途、化学成分可测性等方面对紫地榆的质量标志物(Q-marker)进行预测分析,为明确紫地榆Q-marker和建立科学的质量控制方法提供依据。 As an ethnic medicine unique to Yunnan Province,Geranium strictipes Knuth has been long used in clinical medicine to treat blood in the stool,hemorrhoids,blood dysentery,uterine bleeding,water and fire burns,carbuncle and sore.It is widely used in people of the Yi nationality.Based on research on the chemical constituents and pharmacological effects of Geranium strictipes Knuth,predictive analysis is made of the Q-markers of this drug in terms of original plant phylogeny,specificity of chemical components,traditional efficacy and medicinal properties,new medicinal uses,and measurable chemical components in order to help clarify the quality markers of Geranium strictipes Knuth and establish workable quality control methods.
作者 郗仲玟 田宇柔 冯玉 麻景梅 王鑫国 牛丽颖 XI Zhongwen;TIAN Yurou;FENG Yu;MA Jingmei;WANG Xinguo;NIU Liying(Hebei University of Chinese Medicine,Shijiazhuang Hebei 050091,China;Hebei TCM Formula Granule Innovation Center,Shijiazhuang Hebei 050091,China;Hebei TCM Quality Evaluation&Standardization Engineering Research Center,Shijiazhuang Hebei 050091,China)
出处 《中国药物警戒》 2022年第10期1154-1159,共6页 Chinese Journal of Pharmacovigilance
基金 河北省自然科学基金资助项目(H2019423050) 河北省重点研发计划(20372502D) 中央引导地方科技发展资金项目(206Z2501G)。
关键词 紫地榆 鞣质 酚酸 抗氧化 抗炎镇痛 质量标志物 Geranium strictipes Knuth tannins phenolic acid anti-oxidation anti-inflammatory and analgesic Qmarker
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