营养成分改善环境污染物暴露所致不良健康效应的可能作用机制

Possible mechanisms of nutritional components ameliorating adverse health effects caused by environmental pollutants

环境污染物暴露是影响人类健康的重要危险因素。近年来,有研究证据表明一些营养成分能够改善环境污染物暴露造成的不良健康效应。因此,考虑如何利用这些营养成分进行有效的营养干预,从而减轻环境污染物暴露导致的健康危害,具有重要的公共卫生学意义。本文结合体内、体外实验证据以及人群流行病学相关研究,综述了营养成分改善环境污染物暴露导致的不良健康效应的可能作用机制,为今后深入探讨与环境污染物暴露有关的健康风险评估和营养干预提供方向。

Exposure to environmental pollutants imposes important health risks to human beings.In recent years,emerging evidence has suggested that nutritional components may ameliorate the adverse health effects of environmental pollutants.Therefore,it raises great public health interests in protecting human health from environmental pollutants by nutrition interventions.Considering in vivo and in vitro experimental evidence,as well as epidemiological studies,this paper reviewed the possible mechanisms underlying how nutritional components counteract the adverse health impacts of environmental pollutants,which can provide directions for further studies on health risk assessment and nutrition intervention associated with environmental pollutant exposure.