麻醉气体检测监护仪在胃癌根治术患者中的麻醉效果观察

Observation of anesthetic effect of anesthetic gas monitor in patients undergoing radical gastrectomy

目的探讨麻醉气体检测监护仪在胃癌根治术患者中的麻醉效果,及对患者T淋巴细胞的影响.方法选择2020年2月—2021年2月我院收治的胃癌根治术患者112例,根据干预方法的不同分为两组,各56例.入组患者均采用全身麻醉,对照组给予传统麻醉方式,观察组通过麻醉气体检测监护仪进行麻醉,比较两组麻醉效果、血流动力学、T淋巴细胞水平及麻醉安全性.结果观察组术后苏醒时间、定向力恢复时间均短于对照组(P<0.05).两组患者HR、MAP的组内比较T_(1)>T_(2)>T_(0),IoC的组内比较T0>T2>T1,差异有统计学意义(P<0.05).观察组IoC在T_(1)、T_(2)时组间比较显著低于对照组,差异有统计学意义(P<0.05).观察组术后外周血CD3+、CD4+、CD4+/CD8+高于对照组(P<0.05).观察组不良反应总发生率低于对照组(P<0.05).结论对行胃癌根治术患者通过麻醉气体检测监护仪进行麻醉,能够优化手术指标,利于血流动力学的稳定,有效减少对T淋巴细胞伤害,从而减少术后不良反应的发生,促进术后恢复,值得推广应用.

Objective To investigate the anesthesia effect of anesthesia gas detection monitor in patients with gastric cancer radical resection and its influence on T lymphocytes of patients.Methods From February 2020 to February 2021,112 patients who underwent radical gastrectomy for gastric cancer were selected and randomly divided into two groups with 56 cases in each group.All patients in the group were given general anesthesia,the control group was given traditional anesthesia,and the observation group was anesthetized with an anesthesia gas detection monitor.The anesthesia effect,hemodynamics,T lymphocyte level and anesthesia safety were compared between the two groups.ResultsThe postoperative recovery time and orientation recovery time of the observation group in the observation group were lower than those in the control group(P<0.05).The intra-group comparison of HR and MAP of the two groups was T_(1)>T_(2)>T_(0),and the intra-group comparison of IoC was T_(0)>T_(2)>T_(1),the difference was statistically significant(P<0.05).The IoC of the observation group was significantly lower than that of the control group at T_(1),and T_(2),the difference was statistically significant(P<0.05).The peripheral blood CD3+of the observation group after operation,CD4+,CD4+/CD8+were higher than those in the control group(P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group(P<O.05).Conclusion Anesthesia with an anesthetic gas detection monitor for patients undergoing radical gastrectomy for gastric cancer can optimize the surgical indicators,facilitate the stability of hemodynamics,effectively reduce the damage to T lymphocytes,and thus reduce the occurrence of postoperative adverse reactions,which is beneficial to Postoperative recovery isworthyof promotion andapplication.