摘要
国际基因工程机器大赛(international Genetically Engineered Machine competition,iGEM)是面向世界范围的大学生科技赛事,该比赛旨在推广合成生物学,各个参赛队伍通过使用原始元件和自己设计的新元件来构建新的生物系统,并在活细胞中表达,令其行使某种既定功能。每年的参赛队伍会设计许多新的生物元件(biological part),其长期积累为生物系统的构建提供了便利与创新,其本质上也是生物资源不断丰富的体现。本文从生物资源的角度,重点阐述iGEM比赛生物元件库的发展、分类与特点,让更多人了解生物元件的特征,并在基因工程操作中参考使用,推动元件库的扩充与发展。
The international Genetically Engineered Machine(iGEM)is a science competition for college students around the world. The iGEM competition aims to promote synthetic biology. Each team uses basic biological parts and newly-designed parts to construct biological systems and express them in living cells to perform certain functions. Every year,many new BioBrick parts are designed. They provide innovation and convenience for the construction of biological systems,and reflect the continuous abundance of biological resources. From the perspective of resources,this article focuses on the development,classification and characteristics of the biological part registry,so as to let more people understand the characteristics of BioBrick parts which can further be used in genetic engineering,thus enriching the biological part registry.
作者
朱灵逸
孙明
ZHU Lingyi;SUN Ming(State Key Laboratory of Agricultural Microbiology,College of Life Science and Technology,Huazhong Agricultural University,Wuhan430070,Hubei,China;State Key Laboratory of Microbial Metabolism,College of Life Science and Technology,Shanghai Jiao Tong University,Shanghai 200240,China)
出处
《生物资源》
CAS
2022年第4期355-361,共7页
Biotic Resources
