改良干预程序对消化道出血患者的止血效果

Effect of improved intervention program in patients with gastrointestinal bleeding and how it impacts on coagulation factors

目的分析改良干预程序对消化道出血患者止血效果以及凝血因子的影响。方法选择2019年3月至2021年3月收治的110例消化道出血患者作为研究对象,按数表法将其随机分为对照组(55例,采用常规干预程序)和观察组(55例,采用改良干预程序)。对2组干预后的止血效果、凝血因子的变化情况及满意度进行比较。结果对照组的止血时间短于观察组(t=3.138,P<0.05),输血量多于观察组(t=3.068,P<0.05),止血成功率低于观察组(χ^(2)=7.066,P<0.05),2个月内再出血发生率高于观察组(χ^(2)=6.253,P<0.05);对照组干预后的血浆凝血酶原时间(PT)、活化的部分凝血活酶时间(APTT)、D-二聚体(D-D)水平均高于观察组,血浆纤维蛋白原(FIB)则低于观察组(t=2.895、t=0.666、t=3.032、t=2.991,P<0.05);对照组在干预全面性、亲切度、及时性和规范性的满意度评分均低于观察组(t=3.177、t=3.035、t=2.092、t=3.101,P<0.05)。结论改良干预程序在消化道出血患者中可有效保障止血效果,减少出血再发生率,并改善凝血因子水平,为患者提供了满意的干预服务。

Objective To analyze the effects of improved intervention program on hemostasis and coagulation factors in patients with gastrointestinal bleeding.Methods Totally 110 patients with gastrointestinal bleeding admitted from March 2019 to March 2021 were selected as the research subjects,and the patients were randomly divided into two groups as the table method,the control group(n=55)received routine intervention procedure and the observation group(n=55)received improved intervention procedure.The hemostatic effect,changes in coagulation factors and satisfaction of patients in the two groups after intervention were compared.Results For the control group,the hemostasis duration was shorter than that in the observation group(t=3.138,P<0.05),the of blood transfusion was greater than that in the observation group(t=3.068,P<0.05),the hemostasis rate was lower than that in the observation group(χ^(2)=7.066,P<0.05),and the recurrent bleeding rate within 2 months was higher than that in the observation group(χ^(2)=6.253,P<0.05).Plasma prothrombin time(PT),activated partial thromboplastin time(APTT),D-dimer(D-D)and plasma fibrinogen(FIB)level in the control group after intervention were lower than those in the observation group(t=2.895,t=0.666,t=3.032,t=2.991,P<0.05).The satisfaction scores including comprehensiveness,kindness,timeliness and standardization in the control group were lower than those in the observation group(t=3.177,t=3.035,t=2.092,t=3.101,P<0.05).Conclusion For patients with gastrointestinal bleeding,the improved intervention program supports effectively guaranteeing the hemostatic effect,reducing the recurrent bleeding rate,and improving the level of coagulation factors,thereby providing satisfactory intervention services for patients.