薄层高分辨CT对不同病理类型肺部磨玻璃样病变的定性价值探究

Value of Thin-Layer High-Resolution CT in Qualitative Analysis of Different Pathological Types of Lung Ground-Glass Opacities

目的分析薄层高分辨CT对不同病理类型肺部磨玻璃样病变(GGO)的定性价值。方法选择2019年2月至2020年10月在本院进行治疗的GGO患者89例作为研究对象,根据病理结果将患者分为浸润前病变组(n=17例)、微浸润腺癌组(n=38例,MIA)、浸润性腺癌组(n=34例,IAC),用薄层高分辨CT比较三组患者的病灶大小、形态、实性成分、边缘毛刺、空泡等指标。结果从浸润前病变到MIA再到IAC,病灶大小、实性成分逐级增加(P<0.05),二维比例、三维比例无差异(P>0.05);三组患者的病灶形状、密度、边缘毛刺、内部空泡、胸膜凹陷比较存在差异(P<0.05)。结论从原位癌前病变到微浸润腺癌再到浸润性腺癌,薄层高分辨CT呈现病灶大小、实性、边缘毛刺、分叶、内部空泡、胸膜凹陷逐渐增加,可据此对GGO做病理类型定性分析。

Objective To analyze the value of thin-layer high-resolution CT in qualitative analysis of different pathological types of lung ground-glass opacities(GGO).Methods From February 2019 to October 2020,89 patients with GCO were enrolled in the study.According to the pathological results,the patients were divided into pre-invasive lesion group(17 cases),micro-invasive adenocarcinoma(MIA)group(38 cases),and invasive adenocarcinoma(IAC)group(34 cases).The indexes such as focal size,shape,solid components,spicules of margin,and vacuoles in the three groups were compared.Results The focal size and solid components increased in turn in the pre-invasive lesion group,MIA group,and IAC group(P<0.05).There were no differences in the two-dimensional ratio and three-dimensional ratio(P>0.05).Differences were found in focal shape,density,spicules of margin,internal vacuole,and pleural indentation(P<0.05).Conclusion Thin-layer high-resolution CT images show that focal size,solid lesions,spicules of margin,lobulation,internal vacuoles,and pleural indentation of pre-invasive lesions,MIA,and IAC increase in turn,which provides a basis for qualitative analysis of GGO pathological types.