我国人类精子库安全体系建设的思考

Consideration in the construction of safety system for human sperm banks in China

人类精子库的安全体系直接关联精子库的运行正常性和授精项目的生殖安全性,与子代的生殖健康和优生优育息息相关。我国人类精子库已正式运行20余年,不可避免地暴露出一些安全问题或风险,须予以重视和防范。本文阐述了我国人类精子库运行涉及管理安全、生殖安全和遗传安全等方面可能存在的安全问题或风险,并就人类精子库安全体系建设的可能方向提出见解,包括加强职能部门及医疗机构对人类精子库的支持及监管力度,加快建设人类精子库质量管理体系,促进人类精子库国内外学术交流,推动信息化、人工智能及基因测序等新技术在人类精子库的应用等。重视人类精子库安全体系的建设,防患于未然,对实施高质量的男性生育力保存,保障辅助生殖项目的生殖安全和生殖健康,具有积极现实意义和深远社会影响。

The safety system of human sperm bank is not only directly associated with the working normality of the sperm bank and the reproductive safety of insemination project,but also deeply related to the reproductive health and eugenics of the offspring.Human sperm banks in China have been formally worked for over 20 years.However,some safety problems or risks in sperm banks have been inevitably exposed during the working period.Thus,safety problems or risks of the sperm bank should be fully given attention.In this paper,potential safety problems or risks of the sperm bank were illustrated on aspects of management safety,reproductive safety,and genetic safety.In addition,views on the possible improvement of safety system were given including strengthening supervision for the sperm bank from governmental agencies,promoting academic exchange of sperm banks at home and abroad,and applying new gene sequencing techniques etc.Paying more attention on the construction of the safety system can prevent the potential safety problems or risks in sperm banks,promote high quality male fertility preservation and ensure both reproductive safety and health of assisted reproductive programs.It has positive practical significance and far-reaching social influence.