原发性腮腺非霍奇金淋巴瘤的MRI表现及分析

MRI Manifestations and Analysis of Primary Parotid Non Hodgkin's Lymphoma

目的 探讨原发性腮腺非霍奇金淋巴瘤(NHL)的MRI表现。方法 回顾性分析经病理确诊的19例腮腺NHL患者,分为黏膜相关性淋巴组织淋巴瘤(MALTL)与非黏膜相关性淋巴组织淋巴瘤(非MALTL),并对比MALTL组与非MALTL组在影像上的异同,包括部位、大小、囊变、边界、强化程度、淋巴结转移及Ki-67指数,通过列表卡方检验进行分析。结果 MALTL 7例和非MALTL12例中,单侧分别为4例和10例,双侧分别为3例和2例(P=0.211),浅叶分别为2例和7例,跨深浅叶分别为5例和5例(P=0.21),≥3 cm分别为4例和4例,<3 cm分别为3例和8例(P=0.311),有囊变者分别是5例和1例,无囊变者分别是2例和11例(P=0.004),边界清楚分别是4例和10例,边界不清分别是3例和2例(P=0.211),轻度强化分别是4例和5例,中度及以上强化分别是2例和5例(P=0.515),Ki-67指数高表达分别是1例和10例,低表达分别是6例和2例(P=0.003),颈部淋巴结转移分别是2例和10例(P=0.0211)。结论 MRI检查在诊断原发性腮腺NHL具有一定价值,对于临床诊断与治疗能提供较有意义的辅助信息。

Objective MRI Manifestations of Primary Parotid Non Hodgkin's Lymphoma(NHL).Methods Retrospective analysis of 19 patients with parotid NHL confirmed by pathology,it is divided into mucosa associated lymphoid tissue lymphoma(MALTL)and non mucosa associated lymphoid tissue lymphoma(non MALTL),and compare the similarities and differences of images between MALTL group and non MALTL group,Including location,size,cystic change,border,enhancement degree,lymph node metastasis and Ki-67 index,the analysis was performed by tabular chi square test.Results Among 7 cases of MALTL and 12 cases of non MALTL,4 and 10 cases were unilateral,3 and 2 cases were bilateral(P=0.211),there were 3 and 7 cases in shallow lobe,5 and 5 cases across deep and shallow lobe(P=0.21),4 and 4 cases were≥3 cm,3 and 8 cases were<3 cm(P=0.311),there were 5 and 1 cases with cystic change,2 and 11 cases without cystic change(P=0.004),there were 4 and 10 cases with clear boundary and 3 and 2 cases with unclear boundary(P=0.211),there were 4 and 5 cases of mild enhancement,2 and 5 cases of moderate and above enhancement(P=0.515),the high expression of Ki-67 index was 1 case and 10 cases respectively,the low expression was 6 cases and 2 cases respectively(P=0.003),and the cervical lymph node metastasis was 2 cases and 10 cases respectively(P=0.0211).Conclusion MRI examination has certain value in the diagnosis of primary parotid NHL,It can provide more meaningful auxiliary information for clinical diagnosis and treatment.