中药调控肠道菌群协助抗肿瘤作用

Research progress of traditional Chinese medicine regulating intestinal flora to assist anti-tumor

恶性肿瘤的治疗是亟待解决的全球性难题,也是多年以来医学研究所聚焦的热点。新一代测序技术的出现,揭示了肠道菌群和肿瘤的关联性。肠道菌群不仅参与了肠道肿瘤的发生发展,还与肠外肿瘤有着密切的联系,丰富多样的肠道菌群通过调控机体的免疫、代谢,影响肿瘤的治疗及愈后。传统中药中含有的益生元成份,能够促进有益菌的生长,抑制有害菌的增殖。通过中药调控肠道菌群来抑制肿瘤的发展、提高对肿瘤的治疗效果,已成为肿瘤治疗的新思路和新途径。

The treatment of malignant tumor is a global problem that needs to be solved urgently,and it hasbeen the focus of medical research for many years.The emergence of a new generation of sequencing technology has revealed a link between intestinal flora and tumors.Intestinal flora is not only involved in the occurrence and development of intestinal tumors,but also closely related to extra-intestinal tumors.The abundant and diverse intestinal flora influences the treatment and curative effect of tumors by regulating immunity and metabolism of the body.Most traditional Chinese medicines(TCM)contain prebiotics,which can promote the growth of beneficial bacteria and inhibit the proliferation of harmful bacteria.It has become a new idea and approach for tumor treatment to regulate intestinal flora by traditional Chinese medicine to inhibit tumor development and improve the therapeutic effect of tumor.