脑醒通脉汤治疗脑中风后遗症的效果

Effect of Naoxingtongmai Decoction in Treating Sequelae of Cerebral Apoplexy

目的分析在对脑中风后遗症患者进行治疗的过程中选择脑醒通脉汤进行治疗的效果。方法遵照对比治疗观察的方式展开探究,纳入患者70例,研究时间为2021年2月至2022年1月,按照双盲法分组的方式均分为对照组(35例,行常规治疗)和观察组(35例,以脑醒通脉汤进行治疗)。分析患者的恢复情况。结果对两组患者神经功能评分、日常生活能力评分对比,干预前两组差异无统计学意义,P>0.05,而在干预后,观察组优于对照组,P<0.05。对比两组治疗前后血清炎性因子水平,在肿瘤坏死因子-α水平、白细胞介素-6、白细胞介素-10水平上,治疗前两组差异无统计学意义,P>0.05,而在治疗后,观察组明显优于对照组,P<0.05。对比两组血管内皮因子水平,包括内皮素水平、一氧化氮、内皮衍生超级化因子水平,治疗前两组差异无统计学意义,P>0.05,而在治疗后,观察组明显优于对照组,P<0.05。统计两组治疗期间不良反应情况,观察组不良反应发生率低于对照组,P<0.05。对比两组上肢肌力、下肢肌力以及Fugl-Meyer评分,Barthel指数,在治疗前两组差异无统计学意义,P>0.05,而在治疗后,观察组优于对照组,P<0.05。结论在对脑中风后遗症患者进行治疗的过程中选择脑醒通脉汤进行治疗,可以促使患者受损神经功能以及肢体功能得到有效改善,并可以达到对患者血管内皮功能进行改善的目的,有助于促进患者恢复,且在用药过程中具备较高的安全性,患者不良反应少,可以有效保障对脑中风后遗症患者的治疗效果。

Objective To analyze the effect of naoxingtongmai decoction in the treatment of sequelae of cerebral apoplexy.Methods According to the way of comparative treatment and observation,70 patients were included in the study,which lasted from February 2021 to January 2022.According to the double blind grouping method,they were divided into the control group(35 patients,receiving routine treatment)and the observation group(35 patients,receiving naoxingtongmai decoction).Analyze the recovery of patients.Results There was no difference in neurological function score and daily living ability score between the two groups before intervention(P>0.05),but after intervention,the observation group was better than the control group(P<0.05).The levels of serum inflammatory factors were compared between the two groups before and after treatment.There was no difference in the levels of tumor necrosis factor-α,interleukin-6 and interleukin-10 between the two groups before treatment(P>0.05),but after treatment,the observation group was significantly better than the control group(P<0.05).The levels of vascular endothelial factor(VEGF)in the two groups,including endothelin level,nitric oxide and endothelium derived super factor level,were compared.There was no difference between the two groups before treatment(P>0.05),but after treatment,the observation group was significantly better than the control group(P<0.05).According to the statistics of adverse reactions in the two groups during treatment,the incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05).Compared the muscle strength of upper limbs,lower limbs,Fugl-Meyer score and Barthel index of the two groups,there was no difference between the two groups before treatment(P>0.05),but after treatment,the observation group was superior to the control group(P<0.05).Conclusion In the treatment of patients with sequelae of cerebral apoplexy,selecting naoxingtongmai decoction can effectively improve the impaired nerve function and limb function of patients,and can achieve the purpose of improving the vascular endothelial function of patients,which is helpful for patients to recover,and has high safety in the course of drug use,with fewer adverse reactions.It can effectively guarantee the treatment effect of patients with sequelae of cerebral apoplexy.