3D-TOF-MRA与3D-FIESTA联合3D-TOF-MRA对面肌痉挛术前评估价值比较的Meta分析

Meta analysis of comparison of the preoperative evaluation value of 3D-TOF-MRA and 3D-FIESTA combined with 3D-TOF-MRA for hemifacial spasm

目的以微血管减压术(MVD)为金标准,利用Meta分析方法评价并间接比较3D-TOF-MRA与3D-FIESTA+3D-TOF-MRA对单侧血管压迫性面肌痉挛的术前评估价值。方法计算机检索维普网、万方、知网、PubMed、Cochrane Library、Web of Science、Embase等数据库中的相关文献,采用Review Manager 5.4、Meta-disc 1.4和Stata 12.0软件进行Meta分析,利用相对比值间接比较二者的评估价值。结果经筛选本研究共纳入文献11篇,共计600例患者。Meta分析结果显示,对于单侧血管压迫性面肌痉挛术前评估价值,3D-FIESTA+3D-TOF-MRA与3D-TOF-MRA的Sen合并、Spe合并、+LR、-LR、DOR分别为0.97(95%CI:0.95~0.99),0.85(95%CI:0.81~0.88),6.15(95%CI:4.26~8.87),0.04(95%CI:0.02~0.08),168.23(95%CI:73.19~386.72)与0.89(95%CI:0.85~0.93),0.72(95%CI:0.66~0.78),3.66(95%CI:12.24~5.99),0.13(95%CI:0.06~0.3),29.21(95%CI:10.38~82.17)。3D-FIESTA+3D-TOF-MRA与3D-TOF-MRA间接比较结果RDOR为5.76(95%CI:4.71~7.05)。结论在单侧血管压迫性面肌痉挛术前评估方面,3D-FIESTA+3D-TOF-MRA相较于3D-TOF-MRA具有更高的诊断准确性。

Objective Taking microvacular decompression(MVD)as the gold standard,3D-TOF-MRA and 3D-FIESTA+3D-TOF-MRA were indirectly compared by Meta analysis on unilateral vascular compression hemifacial spasm.Methods The relevant documents in Weipu,Wanfang,CNKI,PubMed,Cochrane Library,Web of Science and Embasewere systematically retrieved.Review Manager 5.4,Meta-disc 1.4 and Stata 12.0 software were used for Meta analysis.The results of indirect comparison were compared by relative ratio.Results After screening,this study included 11 documents with a total of 600 patients.Meta analysis results showed that for the preoperative evaluation value of unilateral vascular compression hemifacial spasm,the Sen merge,Spe merge,+LR,-LR,DOR of 3D-FIESTA+3D-TOF-MRA and 3D-TOF-MRA were respectively 0.97(95%CI:0.95-0.99),0.85(95%CI:0.81-0.88),6.15(95%CI:4.26-8.87),0.04(95%CI:0.02-0.08),168.23(95%CI:73.19-386.72)and 0.89(95%CI:0.85-0.93),0.72(95%CI:0.66-0.78),3.66(95%CI:12.24-5.99),0.13(95%CI:0.06-0.3),29.21(95%CI:10.38-82.17).The RDOR of the indirect comparison between 3D-FIESTA+3D-TOF-MRA and 3D-TOF-MRA was 5.76(95%CI:4.71-7.05).Conclusion Compared with 3D-TOF-MRA,3D-FIESTA+3D-TOF-MRA has higher diagnostic accuracy in the preoperative evaluation of unilateral vascular compression hemifacial spasm.