富血小板血浆治疗粘连性肩关节囊炎患者的疗效

Efficacy of platelet-rich plasma in the treatment of adhesive capsulitis of the shoulder

目的探讨局部注射富血小板血浆(PRP)治疗粘连性肩关节囊炎(ACS)的疗效。方法112例ACS患者分为P组(局部注射PRP,26例)和C组(局部注射复方倍他米松镇痛液,86例)。比较两组治疗前以及治疗后2周、1个月、3个月疼痛数字评分(NRS评分)和肩关节外展主动关节活动度(AROM)。比较两组治疗有效率和镇痛药物使用情况。结果与治疗前比较,两组治疗后各时间点NRS评分降低,肩关节外展AROM增加(P<0.05)。治疗后1个月和3个月两组肩关节外展AROM较治疗后2周增加(P<0.05)。治疗后2周和1个月,P组NRS评分低于C组,而肩关节外展AROM大于C组(P<0.05)。治疗后1个月,P组治疗有效率高于C组(88.46%vs.62.79%)(P<0.05)。治疗后2周和1个月,C组患者塞来昔布使用率高于P组(P<0.05)。结论PRP局部注射可以有效改善肩关节活动度,缓解疼痛,可作为ACS的一种治疗方式。

Objective To observe the efficacy of local injection of platelet-rich plasma(PRP)in the treatment of adhesive capsulitis of the shoulder(ASC).Methods A total of 112 ACS patients were divided into two groups of P(treated with local injection of PRP,26 cases)and C(treated with local injection of compound betamethasone analgesic liquid,86 cases).The pain numeric rating scale score(NRS score)and shoulder abduction active range of motion(AROM)were compared between the two groups at the four time points of before treatment and at 2 weeks,1 month,and 3 months after treatment.The effectiveness rate of treatment and the use of analgesics were compared between the two groups as well.Results Compared with before treatment,the NRS score was decreased and the AROM of shoulder joint abduction was increased in two groups after treatment(P<0.05).The AROM of shoulder joint abduction in two groups was increased at 1 month and 3 months after treatment compared with that at 2 weeks after treatment(P<0.05).At 2 weeks and 1 month after treatment,the NRS score in group P was lower than that in group C,while the AROM in group P was more than that in group C(P<0.05).The effectiveness rate at 1 month after treatment in group P was higher than that in group C(88.46%vs.62.79%)(P<0.05).At 2 weeks and 1 month after treatment,the use rate of celecoxib in group C was higher than that in group P(P<0.05).ConclusionLocal injection of PRP may effectively improve the motion range of the joint and attenuate shoulder pain,which can be used as a treatment method for ACS.