小儿豉翘清热颗粒联合磷酸奥司他韦颗粒治疗儿童流感的疗效及对血清IFN-γ及IL-4水平的影响

The Value of Children’s Chiqiao Qingre Granule Combined with Oseltamivir Phosphates Granules on Serum IFN-γ and IL-4 Levels in Children with Influenza

目的 探究对儿童流行性感冒(简称流感)使用小儿豉翘清热颗粒联合磷酸奥司他韦颗粒治疗的临床效果,及对血清IFN-γ及IL-4水平的影响。方法 选取我院收治的儿童流感患者76例,将其按照随机分组法分为对照组(38例,使用磷酸奥司他韦颗粒治疗)和观察组(38例,使用小儿豉翘清热颗粒联合磷酸奥司他韦颗粒治疗)。对两组的治疗效果进行对比。结果 观察组症状消失时间、不良反应发生率、血清炎性因子水平均优于对照组(P <0.05)。结论 在儿童流感治疗过程中,采用小儿豉翘清热颗粒联合磷酸奥司他韦颗粒治疗能取得较佳的效果,可有效改善临床症状,减少不良反应的出现,降低其炎性反应,促进其康复。

Objective To explore the clinical effect and use value of children’s influenza treated with children’s chiqiao qingre granules combined with oseltamivir phosphate granules.Methods Seventy-six children with influenza in our hospital were randomly divided into control group(38 cases,treated with oseltamivir phosphate granules) and observation group(38 cases,treated with children’s chiqiao qingre granules and oseltamivir phosphate granules).The therapeutic effects of the two groups were compared.Results The time of symptom disappearance,the incidence of adverse reactions and the level of serum inflammatory factors in the observation group were better than those in the control group(P<0.05).Conclusion In the treatment of children’s influenza,the combination of children’s chiqiao qingre granules and oseltamivir phosphate granules can achieve better results,effectively improve their clinical symptoms,reduce the occurrence of adverse reactions,reduce their inflammatory reactions,and promote their recovery.