子午流注针法治疗肺肾气虚型慢性阻塞性肺疾病稳定期的疗效观察

Effect of acupuncture therapy of Midnight-Noon Ebb-Flow on chronic obstructive pulmonary disease with lung-kidney qi deficiency syndrome in stable stage

目的探讨子午流注针法治疗肺肾气虚型慢性阻塞性肺疾病(COPD)稳定期的临床疗效。方法选择2019年4月~2020年5月我院康复科、中医科、呼吸科收治的肺肾气虚型COPD稳定期患者60例,运用随机数字表法按入院顺序分为观察组和对照组,每组30例。两组患者均在西医常规药物治疗基础上,实施针灸治疗。观察组选用子午流注针法,在卯时开穴并实施针灸治疗;对照组在非卯时常规辩证取穴。比较两组的临床疗效、治疗前后中医症候积分、第1秒用力呼气容积(FEV1)、第1秒用力呼气容积百分比(FEV1%)、6分钟步行距离(6 MWT)、mMRC及BODE评分变化情况。结果治疗后,观察组总有效率(93.3%)高于对照组(70.0%),差异具有统计学意义(P<0.05)。治疗前,两组中医症候积分、FEV1、FEV1%、mMRC及BODE评分无明显差异(P>0.05)。治疗后,两组中医症候积分、mMRC及BODE评分均降低,且观察组均低于对照组(P<0.05);两组FEV1、FEV1%、6 MWT均增高,且观察组均高于对照组(P<0.05)。两组患者在整个试验中均无严重不良反应。结论子午流注针法治疗肺肾气虚型慢性阻塞性肺疾病稳定期疗效更显著,可提高临床疗效,减轻患者症状,可在临床推广应用。

Objective To observe the effect of acupuncture therapy of Midnight-Noon Ebb-Flow on chronic obstructive pulmonary disease with lung-kidney qi deficiency syndrome in stable stage.Methods 60 patients were randomly divided into observation group and controlled group,with 30 cases in each group.Patients in both groups were treated with acupuncture on the basis of routine western medicine.The observation group was treated with acupuncture therapy of Midnight-Noon Ebb-Flow,according to this method to select acupoints and carried out acupuncture treatment at Mao period,while the controlled group was treated with routine dialectical acupoint selection at other times.After treatment,the clinical efficacy,TCM symptom integral,FEV1,FEV1%,6MWT,modified MRC dyspnea scale(mMRC)and BODE index were compared between the two groups.Results The total effective rate of the observation group was 93.3%,which was significantly higher than that of the controlled group(70.0%)(P<0.05).Before treatment,there were no significant differences in TCM symptom integral,FEV1,FEV1%,mMRC and BODE index between the two groups(P>0.05).After treatment,the TCM symptom integral,FEV1,FEV1%,mMRC and BODE index of the two groups were decreased,and the observation group was lower than the control group(P<0.05).The FEV1,FEV1%and 6MWT in both groups were increased,and which of the observation group was higher than that of the control group(P<0.05).There were no serious adverse reactions in the two groups during treatment.Conclusion Acupuncture therapy of Midnight-Noon Ebb-Flow is more effective in the treatment of chronic obstructive pulmonary disease of lung-kidney qi deficiency syndrome in stable stage,which can improve the clinical efficacy and reduce the symptoms of patients,and can be popularized in clinical application.