牙髓神经在牙髓组织损伤修复中作用的研究进展

Research Progress on Role of Nerve in Repair of Damaged Dental Pulp

牙髓的防御和自身修复功能是损伤牙髓修复和活髓保存的生物学基础。神经作为牙髓组织的重要组成部分,可能在牙髓损伤后作为始动因素发挥作用。牙髓损伤不仅导致牙髓神经分布、组成结构以及信号分子等发生改变,而且能通过相关信号分子的作用影响周围其他组织细胞。本文就近年来牙髓神经在牙髓组织损伤修复中作用的研究进展进行综述,以期为活髓保存的临床治疗提供参考和理论依据。

The defense and self-repair function of pulp is the biological basis of damaged pulp repair and vital pulp therapy.As an important part of pulp tissue,nerve may play a role as the initiating factor after pulp injury.Pulp injury not only results in the changes of nerve distribution,structure,and signal transduction,but also affects other tissues and cells through related bioactive molecules.This article summarizes and discusses the role of nerve in pulp injury repair in recent years,with aid to provide reference and theoretical guidance for clinical treatment of vital pulp therapy.