对重症急性胰腺炎患者采取乌司他丁联合奥曲肽治疗的意义研究

The Significance of Ulinastatin Combined with Octreotide in the Treatment of Severe Acute Pancreatitis

目的 探讨在重症急性胰腺炎患者采取乌司他丁联合奥曲肽治疗的意义。方法 选取2019年3月至2020年3月在大连市友谊医院急诊科就诊80例重症急性胰腺炎患者,分为试验组和对照组,对照组40例采取奥曲肽治疗,试验组40例采取乌司他丁联合奥曲肽进行治疗,比较两组患者的临床有效率。比较两组患者的临床症状评分,疗效评价评分,不良事件评分比较。结果 试验组临床有效率为90.00%,对照组临床有效率为77.50%,试验组高于对照组,差异有统计学意义(P <0.05)。试验组临床症状评分、疗效评价评分、不良事件评分比较优于对照组,差异有统计学意义(P <0.05)。结论 重症急性胰腺炎患者采取乌司他丁联合奥曲肽治疗临床效果比较好,安全性较高,值得推广。

Objective To explore the significance ulinastatin combined with octreotide in the treatment of severe acute pancreatitis.Methods Eighty patients with severe acute pancreatitis treated in the emergency department of Dalian Friendship Hospital from March 2019 to March 2020 were divided into experimental group and control group.40 patients in the control group were treated with octreotide,and 40 patients the experimental group was treated with ulinastatin combined with octreotide.The clinical effective rates of the two groups were compared.The clinical symptom score,efficacy evaluation score and adverse event score of the two groups were compared.Results The clinical effective rate was 90.00% in the experimental group and 77.50% in the control group.The difference was statistically significant(P<0.05).The clinical symptom score,curative effect evaluation score and adverse event score of the experimental group were better than those of the control group,and the difference was statistically significant(P<0.05).Conclusion Ulinastatin combined with octreotide in the treatment of patients with severe acute pancreatitis has good clinical effect and high safety,which is worthy of promotion.